Tissue expression of UPP2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	UPP2
Gene description	Uridine phosphorylase 2
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (kidney, liver)
GTEx:	Tissue enhanced (kidney, liver)
FANTOM5:	Tissue enhanced (pituitary gland)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (kidney, liver)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (kidney, liver)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pituitary gland)

GENE INFORMATION
Gene name	UPP2 (HGNC Symbol)
Synonyms	UDRPASE2, UP2, UPASE2
Description	Uridine phosphorylase 2 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q24.1
Chromosome location (bp)	157876702 - 158136154
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000007001 (version 83.38)
Entrez gene	151531
UniProt	O95045 (UniProt - Evidence at protein level)
neXtProt	NX_O95045
Antibodypedia	UPP2 antibodies

PROTEIN BROWSER

UPP2-001	UPP2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UPP2-001 ENSP00000005756 ENST00000005756	O95045 [Direct mapping] Uridine phosphorylase 2 Show all	Enzymes ENZYME proteins Transferases SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0004850 [uridine phosphorylase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006206 [pyrimidine nucleobase metabolic process] GO:0009116 [nucleoside metabolic process] GO:0009166 [nucleotide catabolic process] GO:0016763 [transferase activity, transferring pentosyl groups] GO:0043097 [pyrimidine nucleoside salvage] GO:0044206 [UMP salvage] GO:0044281 [small molecule metabolic process] GO:0045098 [type III intermediate filament] GO:0046108 [uridine metabolic process] GO:0046135 [pyrimidine nucleoside catabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	317 aa 35.5 kDa	No	0
UPP2-002 ENSP00000474090 ENST00000605860	O95045 [Direct mapping] Uridine phosphorylase 2 Show all	Enzymes ENZYME proteins Transferases SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0004850 [uridine phosphorylase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006206 [pyrimidine nucleobase metabolic process] GO:0009116 [nucleoside metabolic process] GO:0009166 [nucleotide catabolic process] GO:0016763 [transferase activity, transferring pentosyl groups] GO:0043097 [pyrimidine nucleoside salvage] GO:0044206 [UMP salvage] GO:0044281 [small molecule metabolic process] GO:0045098 [type III intermediate filament] GO:0046108 [uridine metabolic process] GO:0046135 [pyrimidine nucleoside catabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	374 aa 41.6 kDa	No	0