We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Fields »
 

Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
ABOUT
HELP
BLOG
  • THE HUMAN PROTEOME
  • THE HUMAN TISSUES
  • THE HUMAN CELL
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
    • NEWS
    • BLOG
    • EVENTS
    • PRESS ROOM
    • LEARN
    • DICTIONARY
    • METHODS
    • CELL LINES
  • THE PROJECT
  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • PUBLICATION DATA
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • LINKS
  • CONTACT
  • TECHNICAL DATA
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • DOWNLOADABLE DATA
  • HELP & FAQ
  • LICENCE & CITATION
  • PRIVACY STATEMENT
  • RELEASE HISTORY
MDH1
  • TISSUE

  • premium

    CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA LIVER

GENE/PROTEIN

Antibody validation


Dictionary

Liver

Tissue proteome

Liver

LIVER - Expression summary

Protein expressioni

The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.

h
m
l
n

RNA expressioni

RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.

Read more

HPA:117.8TPM
GTEx:36.4RPKM
FANTOM5:178.5Tags Per Million

LIVER - Annotated protein expressioni

The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.

Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.

The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.

For histological reference, view the histological dictionary.

Annotated protein
expression

Bile duct cells:Medium
Hepatocytes:Medium
 

Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.

Read more

Antibody HPA027296

 

Antibody HPA054276

 

Antibody CAB047333

 

Bile duct cells

Medium   Low   Low  

Hepatocytes

Medium   Medium   Medium  
     
     
     

LIVER - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Read more

Average TPM

117.8

N/A Female, age 60
Sample 1
TPM: 89.0
overview Male, age 54
Sample 2
TPM: 82.2
Cell types%
Hepatocytes: 80
Fibroblasts: 15
Other cell types: 5
overview Male, age 74
Sample 3
TPM: 111.6
Cell types%
Hepatocytes: 85
Fibroblasts: 5
Other cell types: 10
overview Female, age 62
Sample 4
TPM: 139.2
Cell types%
Hepatocytes: 70
Fibroblasts: 10
Other cell types: 20
overview Male, age 78
Sample 5
TPM: 119.0
Cell types%
Hepatocytes: 75
Fibroblasts: 5
Other cell types: 20
overview Male, age 53
Sample 6
TPM: 161.0
Cell types%
Hepatocytes: 80
Fibroblasts: 5
Other cell types: 15
overview Male, age 77
Sample 7
TPM: 113.6
Cell types%
Hepatocytes: 75
Fibroblasts: 5
Other cell types: 20
overview Female, age 72
Sample 8
TPM: 122.3
Cell types%
Hepatocytes: 50
Fibroblasts: 10
Other cell types: 40
overview Male, age 70
Sample 9
TPM: 110.1
Cell types%
Hepatocytes: 65
Fibroblasts: 10
Other cell types: 25
overview Female, age 23
Sample 10
TPM: 129.6
Cell types%
Hepatocytes: 70
Fibroblasts: 5
Other cell types: 25

LIVER - GTEx RNA-seqi

RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.

Read more

Average RPKM

36.4

GTEx sample id

RPKM

 

Liver

Liver
RPKM: 36.4
Samples: 119

Max RPKM: 174.5
Min RPKM: 7.7
Std RPKM: 16.9
Median RPKM: 33.5
GTEX-13N11-0926-SM-5IJG2 174.5
GTEX-Y5LM-0426-SM-4VBRO 83.1
GTEX-1497J-0726-SM-5Q5D1 68.8
GTEX-YB5E-0326-SM-5IFHU 64.8
GTEX-13SLX-1226-SM-5S2Q6 64.3
GTEX-S32W-1926-SM-4AD63 62.0
GTEX-13FTW-1126-SM-5J2NV 57.5
GTEX-11EQ9-0526-SM-5A5JZ 56.3
GTEX-14C38-1526-SM-5RQJ7 52.5
GTEX-QESD-2026-SM-447BI 50.8
GTEX-R53T-0326-SM-48FEC 50.8
GTEX-RTLS-1326-SM-46MUN 47.9
GTEX-UPIC-0926-SM-4IHLV 47.5
GTEX-12WSG-0626-SM-5FQTQ 46.6
GTEX-14AS3-0126-SM-5Q5F4 46.4
GTEX-WFON-1726-SM-4LVMQ 46.4
GTEX-145MF-0826-SM-5QGQA 45.6
GTEX-QEL4-1226-SM-447A4 45.6
GTEX-S4Z8-0526-SM-4AD4T 45.4
GTEX-13113-1326-SM-5GCOI 44.9
GTEX-13NZ9-1326-SM-5MR3V 44.7
GTEX-1399T-0826-SM-5IFES 43.4
GTEX-P78B-1326-SM-3P611 43.4
GTEX-ZYY3-0626-SM-5NQ6W 43.3
GTEX-ZTPG-1426-SM-51MT3 42.6
GTEX-OOBJ-0826-SM-3NB2K 42.5
GTEX-ZAB5-0426-SM-5CVMI 42.5
GTEX-139TS-1426-SM-5IFJD 42.4
GTEX-ZVP2-0626-SM-51MSO 42.1
GTEX-X4EP-1026-SM-4QAS5 41.5
GTEX-RM2N-1926-SM-48FCU 41.1
GTEX-13FLV-0326-SM-5N9DJ 40.9
GTEX-U3ZN-0226-SM-3DB8D 40.4
GTEX-REY6-1226-SM-48FDR 39.8
GTEX-Q734-0326-SM-48U15 39.6
GTEX-1399R-1226-SM-5P9GF 39.4
GTEX-PX3G-0826-SM-48TZS 39.2
GTEX-146FH-1526-SM-5NQBU 39.0
GTEX-ZF2S-3026-SM-4WWCH 38.0
GTEX-ZZPU-0426-SM-5GZYH 37.6
GTEX-139YR-0226-SM-5IFEM 37.5
GTEX-QDVN-0826-SM-48TZ2 37.4
GTEX-11OF3-0726-SM-5BC4Z 36.9
GTEX-ZVT3-1626-SM-5GU66 36.9
GTEX-XOTO-0826-SM-4B65O 36.7
GTEX-13OW6-2626-SM-5IFF2 36.6
GTEX-147F4-1426-SM-5LUA8 36.2
GTEX-QV44-0326-SM-4R1KD 36.1
GTEX-ZF29-2026-SM-4WWB7 36.1
GTEX-147JS-1126-SM-5RQIW 36.0
GTEX-RU72-1426-SM-46MUF 35.9
GTEX-12KS4-1326-SM-5LUB3 35.7
GTEX-145MO-2326-SM-5NQ9K 35.7
GTEX-12WSI-0226-SM-5GCNA 35.3
GTEX-T6MN-1226-SM-3NMA5 35.3
GTEX-139TU-0826-SM-5IJFG 35.1
GTEX-13FTZ-0726-SM-5IFFY 34.9
GTEX-12WSM-0726-SM-5GCOW 34.5
GTEX-13NYB-1026-SM-5IFH3 33.9
GTEX-12WSD-1426-SM-5GCN9 33.5
GTEX-11DXZ-0126-SM-5EGGY 32.7
GTEX-14DAQ-1726-SM-5S2R2 32.7
GTEX-11WQC-0726-SM-5EQMR 32.5
GTEX-ZPU1-0826-SM-57WG2 32.5
GTEX-12696-0826-SM-5EGGE 32.4
GTEX-12WSL-0226-SM-5CVMJ 32.4
GTEX-X4EO-1126-SM-4QARQ 32.2
GTEX-Y5V5-0926-SM-4VBPZ 32.2
GTEX-14753-1626-SM-5NQ9L 32.1
GTEX-YECK-1926-SM-4W21H 32.1
GTEX-1269C-0626-SM-5FQSS 31.9
GTEX-SJXC-1226-SM-4DM78 31.7
GTEX-132NY-0926-SM-5P9G3 31.5
GTEX-QEG4-1826-SM-4R1JN 31.3
GTEX-WYVS-1926-SM-4PQZ2 31.2
GTEX-14E1K-0326-SM-5S2PE 31.1
GTEX-UTHO-2426-SM-4JBHD 31.1
GTEX-14A5I-1726-SM-5QGQ5 31.0
GTEX-WQUQ-1926-SM-4OOSA 31.0
GTEX-13PVR-0126-SM-5S2PY 30.8
GTEX-Z9EW-0426-SM-5CVM9 30.3
GTEX-UPK5-1426-SM-4JBHH 30.1
GTEX-11NV4-1326-SM-5HL6V 29.5
GTEX-1212Z-0226-SM-59HLF 29.0
GTEX-131XE-0326-SM-5LZVO 28.4
GTEX-13VXU-0926-SM-5IFFH 28.2
GTEX-X3Y1-2726-SM-4PQZH 28.1
GTEX-S33H-1626-SM-4AD68 27.7
GTEX-TKQ2-1726-SM-4DXUP 27.7
GTEX-ZVT4-0626-SM-5E45T 27.7
GTEX-ZAB4-0826-SM-5LU9D 27.4
GTEX-11ZVC-0726-SM-5FQT9 27.2
GTEX-ZYT6-0626-SM-5E45V 27.1
GTEX-13112-1426-SM-5EGH8 26.5
GTEX-131XH-0626-SM-5LZWH 26.5
GTEX-RWSA-1426-SM-47JXA 26.5
GTEX-VUSG-0126-SM-4KL1X 26.5
GTEX-X261-1726-SM-4PQYT 26.2
GTEX-144GM-1326-SM-5LU5E 26.1
GTEX-13N2G-0926-SM-5IFGJ 25.9
GTEX-YEC4-0826-SM-5P9FV 24.9
GTEX-131YS-1626-SM-5HL6C 24.5
GTEX-11NUK-1226-SM-5P9GM 24.4
GTEX-13QJC-0726-SM-5RQJK 24.3
GTEX-YFC4-1526-SM-5IFJS 24.0
GTEX-11ZTS-1426-SM-5EQMM 23.3
GTEX-X4XY-1626-SM-46MVN 23.1
GTEX-11DXY-0526-SM-5EGGQ 22.8
GTEX-13O3O-1826-SM-5IFGW 22.8
GTEX-XBEC-1526-SM-4AT68 22.4
GTEX-RN64-1826-SM-48FDV 21.2
GTEX-RNOR-1426-SM-48FDJ 20.6
GTEX-WZTO-0626-SM-4PQYY 20.5
GTEX-145LU-1326-SM-5LU9N 20.0
GTEX-Q2AG-1126-SM-48U1P 19.8
GTEX-11GSP-0626-SM-5986T 18.0
GTEX-13NZB-0626-SM-5IFH6 17.7
GTEX-11ZUS-2526-SM-59872 17.5
GTEX-12ZZZ-1326-SM-59HKW 7.7
Show all

LIVER - FANTOM5 CAGEi

Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.

Read more

Average Tags Per Million

178.5

FANTOM5 sample id

Sample description

Tags Per Million

Liver
Tags Per Million: 178.5
FF:10018-101C9 64,69,70 years, mixed 178.5

Contact

  • BLOG
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.