Tissue expression of AP3D1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	AP3D1
Gene description	Adaptor-related protein complex 3, delta 1 subunit
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	AP3D1 (HGNC Symbol)
Synonyms	ADTD
Description	Adaptor-related protein complex 3, delta 1 subunit (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	2100988 - 2164465
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000065000 (version 83.38)
Entrez gene	8943
UniProt	O14617 (UniProt - Evidence at protein level)
neXtProt	NX_O14617
Antibodypedia	AP3D1 antibodies

PROTEIN BROWSER

AP3D1-001	AP3D1-002	AP3D1-011	AP3D1-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AP3D1-001 ENSP00000347416 ENST00000355272	O14617 [Direct mapping] AP-3 complex subunit delta-1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005215 [transporter activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005765 [lysosomal membrane] GO:0005794 [Golgi apparatus] GO:0006726 [eye pigment biosynthetic process] GO:0006886 [intracellular protein transport] GO:0008089 [anterograde axon cargo transport] GO:0008565 [protein transporter activity] GO:0010008 [endosome membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0019882 [antigen processing and presentation] GO:0030117 [membrane coat] GO:0030424 [axon] GO:0032438 [melanosome organization] GO:0033365 [protein localization to organelle] GO:0035646 [endosome to melanosome transport] GO:0043195 [terminal bouton] GO:0048007 [antigen processing and presentation, exogenous lipid antigen via MHC class Ib] GO:0048490 [anterograde synaptic vesicle transport] GO:0048499 [synaptic vesicle membrane organization] GO:0051138 [positive regulation of NK T cell differentiation] GO:0061088 [regulation of sequestering of zinc ion] GO:0072657 [protein localization to membrane] Show all	1215 aa 136.7 kDa	No	0
AP3D1-002 ENSP00000344055 ENST00000345016	O14617 [Direct mapping] AP-3 complex subunit delta-1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005215 [transporter activity] GO:0005488 [binding] GO:0005654 [nucleoplasm] GO:0005765 [lysosomal membrane] GO:0005794 [Golgi apparatus] GO:0006726 [eye pigment biosynthetic process] GO:0006886 [intracellular protein transport] GO:0008089 [anterograde axon cargo transport] GO:0008565 [protein transporter activity] GO:0010008 [endosome membrane] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016192 [vesicle-mediated transport] GO:0030117 [membrane coat] GO:0032438 [melanosome organization] GO:0035646 [endosome to melanosome transport] GO:0048490 [anterograde synaptic vesicle transport] GO:0061088 [regulation of sequestering of zinc ion] GO:0072657 [protein localization to membrane] Show all	1153 aa 130.2 kDa	No	0
AP3D1-011 ENSP00000468449 ENST00000586370	K7ERW8 [Direct mapping] AP-3 complex subunit delta-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		155 aa 17 kDa	No	0
AP3D1-012 ENSP00000466267 ENST00000589369	K7ELX8 [Direct mapping] AP-3 complex subunit delta-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		193 aa 20.7 kDa	No	0