Tissue expression of SLC16A8 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SLC16A8
Gene description	Solute carrier family 16 (monocarboxylate transporter), member 8
Protein class	Plasma proteins Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Tissue enriched (retina)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (retina)

GENE INFORMATION
Gene name	SLC16A8 (HGNC Symbol)
Synonyms	MCT3, REMP
Description	Solute carrier family 16 (monocarboxylate transporter), member 8 (HGNC Symbol)
Entrez gene summary	SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010]
Chromosome	22
Cytoband	q13.1
Chromosome location (bp)	38078134 - 38084093
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000100156 (version 83.38)
Entrez gene	23539
UniProt	O95907 (UniProt - Evidence at transcript level)
neXtProt	NX_O95907
Antibodypedia	SLC16A8 antibodies

PROTEIN BROWSER

SLC16A8-001	SLC16A8-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC16A8-001 ENSP00000321735 ENST00000320521	O95907 [Direct mapping] Monocarboxylate transporter 3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Plasma proteins Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006090 [pyruvate metabolic process] GO:0007596 [blood coagulation] GO:0008028 [monocarboxylic acid transmembrane transporter activity] GO:0009925 [basal plasma membrane] GO:0015129 [lactate transmembrane transporter activity] GO:0015293 [symporter activity] GO:0015718 [monocarboxylic acid transport] GO:0015727 [lactate transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0035879 [plasma membrane lactate transport] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] GO:0050900 [leukocyte migration] GO:0055085 [transmembrane transport] Show all	504 aa 52.3 kDa	No	>9
SLC16A8-003 ENSP00000409547 ENST00000427592	B0QYL4 [Direct mapping] Monocarboxylate transporter 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0005887 [integral component of plasma membrane] GO:0015129 [lactate transmembrane transporter activity] GO:0035879 [plasma membrane lactate transport] Show all	97 aa 10.1 kDa	No	2