We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Fields »
 

Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
ABOUT
HELP
BLOG
  • THE HUMAN PROTEOME
  • THE HUMAN TISSUES
  • THE HUMAN CELL
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
    • NEWS
    • BLOG
    • EVENTS
    • PRESS ROOM
    • LEARN
    • DICTIONARY
    • METHODS
    • CELL LINES
  • THE PROJECT
  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • PUBLICATION DATA
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • LINKS
  • CONTACT
  • TECHNICAL DATA
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • DOWNLOADABLE DATA
  • HELP & FAQ
  • LICENCE & CITATION
  • PRIVACY STATEMENT
  • RELEASE HISTORY
AAGAB
  • premium

    TISSUE

  • premium

    CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA SPLEEN

GENE/PROTEIN

Antibody validation


Dictionary

Spleen

Tissue proteome

Spleen

SPLEEN - Expression summary

Protein expressioni

The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.

h
m
l
n

RNA expressioni

RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.

Read more

HPA:21.8TPM
GTEx:10.5RPKM
FANTOM5:38.1Tags Per Million

SPLEEN - Annotated protein expressioni

The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.

Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.

The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.

For histological reference, view the histological dictionary.

Annotated protein
expression

Cells in red pulp:Medium
Cells in white pulp:High
 

Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.

Read more

Antibody HPA039371

 

Antibody HPA040174

 

Cells in red pulp

Medium   Medium  

Cells in white pulp

High   Medium  
   
   
   

SPLEEN - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Read more

Average TPM

21.8

overview Female, age 60
Sample 1
TPM: 21.6
Cell types%
Lymphocytes: 40
Macrophages: 30
Endothelial cells: 15
Fibroblasts: 5
Other cell types: 10
overview Male, age 17
Sample 2
TPM: 16.7
Cell types%
Lymphocytes: 40
Macrophages: 35
Endothelial cells: 15
Fibroblasts: 5
Other cell types: 5
overview Male, age 20
Sample 3
TPM: 15.6
Cell types%
Lymphocytes: 40
Macrophages: 30
Endothelial cells: 15
Fibroblasts: 5
Other cell types: 10
overview Female, age 19
Sample 4
TPM: 19.9
Cell types%
Lymphocytes: 40
Macrophages: 30
Endothelial cells: 15
Fibroblasts: 10
Other cell types: 5
overview Female, age 65
Sample 5
TPM: 35.3
Cell types%
Lymphocytes: 35
Macrophages: 30
Endothelial cells: 20
Fibroblasts: 10
Other cell types: 5

SPLEEN - GTEx RNA-seqi

RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.

Read more

Average RPKM

10.5

GTEx sample id

RPKM

 

Spleen

Spleen
RPKM: 10.5
Samples: 104

Max RPKM: 14.3
Min RPKM: 7.5
Std RPKM: 1.3
Median RPKM: 10.4
GTEX-ZPU1-1026-SM-4YCEQ 14.3
GTEX-QMRM-0226-SM-4R1K7 14.0
GTEX-XMK1-0126-SM-4B65F 13.6
GTEX-11P81-1326-SM-5GU5S 13.3
GTEX-VJYA-0126-SM-4KL1P 13.3
GTEX-13N11-0126-SM-5KM2Z 13.2
GTEX-PX3G-0926-SM-48U12 13.0
GTEX-146FQ-0626-SM-5LU9U 12.8
GTEX-XXEK-0126-SM-4BRVU 12.4
GTEX-U3ZN-0126-SM-4DXUM 12.3
GTEX-Y5LM-0326-SM-4VBRN 12.3
GTEX-132QS-0226-SM-5IFFZ 12.2
GTEX-117YX-2126-SM-5GIEL 12.0
GTEX-11P7K-0426-SM-5BC5H 11.9
GTEX-ZVZP-0726-SM-59HKA 11.9
GTEX-146FR-1926-SM-5NQA6 11.8
GTEX-ZV6S-0826-SM-5NQ6Z 11.8
GTEX-11DXX-0726-SM-5H12X 11.7
GTEX-11NSD-0426-SM-5N9CR 11.7
GTEX-POMQ-0126-SM-48TD6 11.7
GTEX-139T6-0226-SM-5IFGZ 11.5
GTEX-144GN-2126-SM-5O99D 11.5
GTEX-ZP4G-0326-SM-4YCEF 11.4
GTEX-U4B1-0526-SM-4DXTK 11.3
GTEX-11VI4-0126-SM-5GU6Z 11.2
GTEX-1399S-0226-SM-5IFFG 11.2
GTEX-QV31-0126-SM-447BP 11.2
GTEX-12WSG-0926-SM-5EGIH 11.1
GTEX-12WSJ-0526-SM-5GCOZ 11.1
GTEX-131XE-1126-SM-5EGHW 11.1
GTEX-QCQG-0226-SM-48U28 11.1
GTEX-13CF3-0226-SM-5J1NW 11.0
GTEX-13X6H-0726-SM-5Q5BX 11.0
GTEX-1122O-0526-SM-5N9DM 10.9
GTEX-11XUK-0426-SM-5EQML 10.9
GTEX-147F3-0126-SM-5NQBJ 10.9
GTEX-O5YT-0926-SM-48TDG 10.9
GTEX-XGQ4-0126-SM-4AT4H 10.9
GTEX-ZYWO-0226-SM-5GZX3 10.9
GTEX-ZDTT-1026-SM-5KM19 10.8
GTEX-12BJ1-0726-SM-5EGGF 10.7
GTEX-145MN-0126-SM-5RQHY 10.7
GTEX-QV44-0126-SM-4R1KH 10.7
GTEX-R55G-0226-SM-48FEI 10.7
GTEX-ZLFU-0526-SM-4WWBN 10.7
GTEX-11LCK-0126-SM-5A5M5 10.6
GTEX-QLQW-0126-SM-447BK 10.6
GTEX-131XG-0426-SM-5IFGD 10.5
GTEX-13S86-0126-SM-5S2PI 10.5
GTEX-YFCO-0926-SM-5LUA5 10.5
GTEX-ZZPU-0126-SM-5E446 10.5
GTEX-14DAR-0326-SM-5S2PS 10.4
GTEX-U3ZH-0126-SM-4DXUK 10.4
GTEX-1211K-0426-SM-5FQTP 10.3
GTEX-13111-0126-SM-5EGHO 10.3
GTEX-13U4I-1626-SM-5IFFR 10.3
GTEX-PW2O-0126-SM-48TC8 10.3
GTEX-12WSK-0126-SM-5GCO7 10.2
GTEX-13PVR-0326-SM-5RQJY 10.2
GTEX-WHWD-0126-SM-4OORS 10.2
GTEX-Z9EW-0726-SM-5HL9H 10.2
GTEX-OOBJ-0926-SM-48TDO 10.1
GTEX-PLZ6-0126-SM-48TC6 10.1
GTEX-Q2AH-0226-SM-48U1I 10.1
GTEX-RUSQ-0126-SM-47JWV 10.1
GTEX-XQ8I-1726-SM-4BOQB 10.1
GTEX-ZVP2-0526-SM-51MSC 10.1
GTEX-1399R-0226-SM-5IJGG 10.0
GTEX-139YR-0426-SM-5IFFV 10.0
GTEX-13FH7-1326-SM-5IFG8 10.0
GTEX-X4LF-0226-SM-4QAS8 10.0
GTEX-YB5E-0426-SM-5IFHR 9.9
GTEX-YEC4-0126-SM-4W21T 9.9
GTEX-ZYFG-0726-SM-5GIDX 9.9
GTEX-12WSN-0126-SM-5DUX5 9.8
GTEX-OIZH-0926-SM-48TBR 9.8
GTEX-T5JW-0126-SM-4DM6K 9.8
GTEX-XAJ8-0126-SM-47JYG 9.8
GTEX-P4PP-0926-SM-48TBZ 9.7
GTEX-P4QS-0926-SM-48TBS 9.7
GTEX-WFON-0126-SM-4LVM9 9.6
GTEX-ZAB5-0526-SM-5CVMU 9.6
GTEX-13VXT-1326-SM-5LU3Y 9.5
GTEX-UJHI-0126-SM-4IHLP 9.5
GTEX-XUJ4-0226-SM-4BOP8 9.5
GTEX-XV7Q-0126-SM-4BRVK 9.5
GTEX-11EQ9-0426-SM-5A5JY 9.4
GTEX-Y3IK-0126-SM-4WWE9 9.4
GTEX-XPVG-0626-SM-4B65B 9.2
GTEX-Y8LW-0126-SM-4VBS1 9.2
GTEX-YB5K-1926-SM-4VDT4 9.1
GTEX-ZLWG-0426-SM-4WWFA 9.0
GTEX-S3XE-0626-SM-4AD6B 8.9
GTEX-UPK5-1626-SM-4JBHI 8.9
GTEX-X3Y1-0126-SM-4PQZA 8.8
GTEX-13PL7-1126-SM-5MR5O 8.7
GTEX-Y3I4-0126-SM-4TT26 8.7
GTEX-W5WG-0626-SM-4SOID 8.6
GTEX-QDVN-0526-SM-48TZ4 8.4
GTEX-S4Z8-0226-SM-4AD5K 8.4
GTEX-Y114-0726-SM-4TT6U 8.4
GTEX-Q734-0226-SM-48U1A 8.1
GTEX-14E6E-1226-SM-5S2R5 8.0
GTEX-X585-1826-SM-4QAS3 7.5
Show all

SPLEEN - FANTOM5 CAGEi

Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.

Read more

Average Tags Per Million

38.1

FANTOM5 sample id

Sample description

Tags Per Million

Spleen
Tags Per Million: 38.1
FF:10025-101D7 39,50,70 years, male 38.1

Contact

  • BLOG
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.