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ASF1B

GENERAL INFORMATION

Gene name

 ASF1B

Gene description

 Anti-silencing function 1B histone chaperone

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enhanced (testis, appendix)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, appendix)

GENE INFORMATION

Gene name

 ASF1B (HGNC Symbol)

Synonyms

 FLJ10604

Description

 Anti-silencing function 1B histone chaperone (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. [provided by RefSeq, Jul 2008]

Chromosome

 19

Cytoband

 p13.12

Chromosome location (bp)

 14119509 - 14136956

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105011 (version 83.38)

Entrez gene

 55723

UniProt

 Q9NVP2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NVP2

Antibodypedia

 ASF1B antibodies

PROTEIN BROWSER
ASF1B-001
ASF1B-002
ASF1B-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ASF1B-001
ENSP00000263382
ENST00000263382
Q9NVP2 [Direct mapping]
Histone chaperone ASF1B
A0A024R7G4 [Target identity:100%; Query identity:100%]
ASF1 anti-silencing function 1 homolog B (S. cerevisiae), isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000785 [chromatin]
GO:0000790 [nuclear chromatin]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006333 [chromatin assembly or disassembly]
GO:0006334 [nucleosome assembly]
GO:0006335 [DNA replication-dependent nucleosome assembly]
GO:0006336 [DNA replication-independent nucleosome assembly]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0016568 [chromatin modification]
GO:0030154 [cell differentiation]
GO:0042393 [histone binding]
GO:0043234 [protein complex]
Show all
 202 aa
22.4 kDa 		No 0
ASF1B-002
ENSP00000466257
ENST00000474890
K7ELW9 [Direct mapping]
Histone chaperone ASF1B
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006333 [chromatin assembly or disassembly]
Show all
 165 aa
18.3 kDa 		No 0
ASF1B-005
ENSP00000468513
ENST00000592798
K7ES22 [Direct mapping]
Histone chaperone ASF1B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006333 [chromatin assembly or disassembly]
Show all
 143 aa
15.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.