The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Most normal tissues displayed moderate nuclear and occasional cytoplasmic positivity. Strong nuclear staining was observed in Purkinje cells while ovarian follicles and adrenal cortex showed strong cytoplasmic immunoreactivity. Pneumocytes, bile ducts, pancreatic islets, thyroid, breast and glial cells were negative.
Most normal tissues displayed weak to moderate cytoplasmic and/or nuclear/membranous staining. Subset of cells in renal tubules and lymphoid tissues were strongly stained. Lung, stomach, liver, breast and uterus were negative.