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Malignant cells showed moderate to strong cytoplasmic staining. Most renal and liver cancers were negative.
GENE INFORMATION
Gene name
CACYBP (HGNC Symbol)
Synonyms
S100A6BP, SIP
Description
Calcyclin binding protein (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]