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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

AGMAT

Gene description

Agmatine ureohydrolase (agmatinase)

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (kidney)
GTEx:Tissue enhanced (kidney, liver)
FANTOM5:Group enriched (liver, small intestine, kidney, colon)

Protein evidence

Evidence at protein level

Protein expression

High cytoplasmic expression in the GI-tract and renal tubules.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 2 antibodies.
HPA026443 , HPA028321
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney, liver)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (liver, small intestine, kidney, colon)

GENE INFORMATION

Gene name

AGMAT (HGNC Symbol)

Synonyms

FLJ23384

Description

Agmatine ureohydrolase (agmatinase) (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

p36.21

Chromosome location (bp)

15572353 - 15585110

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116771 (version 83.38)

Entrez gene

79814

UniProt

Q9BSE5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BSE5

Antibodypedia

AGMAT antibodies

PROTEIN BROWSER

AGMAT-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGMAT-001
ENSP00000364986
ENST00000375826
Q9BSE5 [Direct mapping]
Agmatinase, mitochondrial
A0A024QZ78 [Target identity:100%; Query identity:100%]
Agmatine ureohydrolase (Agmatinase), isoform CRA_a
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Enzymes
   ENZYME proteins
   Hydrolases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
GO:0006595 [polyamine metabolic process]
GO:0008295 [spermidine biosynthetic process]
GO:0008783 [agmatinase activity]
GO:0016813 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines]
GO:0033388 [putrescine biosynthetic process from arginine]
GO:0034641 [cellular nitrogen compound metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
GO:0097055 [agmatine biosynthetic process]
Show all
352 aa
37.7 kDa
No 0

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