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Show complete data for human cells assay. The location(s) are highlighted in the illustration on the right.
RNA cell categoryi
The cell lines in the Human Protein Atlas have been analyzed by RNA-seq to estimate the transcript abundance of each protein-coding gene. The RNA-seq data was then used to classify all genes according to their cell line-specific expression into one of six different categories, defined based on the total set of all TPM values in all analyzed cell lines.
Protein evidence scores are generated from several independent sources and are classified as evidence at i) protein level, ii) transcript level, iii) no evidence, or iv) not available.
Evidence at protein level
Main locationi
The main location is characterized by presence in all tested cell lines and/or increased intensity compared to other locations. It is highlighted in the illustration to the right. If available, links to overrepresentation analyses in Reactome, a free, open-source, curated and peer reviewed biological pathway database, are provided. An analysis is done for the corresponding gene set of the proteome localizing to the main and additional locations of the protein on this page, respectively.
Not available
DATA RELIABILITY
Reliability scorei
A reliability score is set for all genes and indicates the level of reliability of the analyzed protein expression pattern based on available protein/RNA/gene characterization data. The reliability of the annotated protein expression data is also scored depending on similarity in immunostaining patterns and consistency with available experimental gene/protein characterization data in the UniProtKB/Swiss-Prot database.
Below is an overview of RNA expression data generated in the HPA project. The analyzed cell lines are divided into 12 color-coded groups according to the organ they were obtained from. By clicking the toolbars in the top right corner it is possible to sort the cell lines in the chart by different criteria: the organ and the origin that the cell line was obtained from, the category of the cell line according to cellosaurus, alphabetically or by descending RNA expression. Detailed information about a specific cell line can be accessed by hovering over the corresponding bar in the chart. The RNA-sequencing results generated in the HPA are reported as number of Transcripts per Kilobase Million (TPM). In the Human Protein Atlas a TPM value of 1.0 is defined as a treshhold for expression of the corresponding protein.
The cell lines in the Human Protein Atlas have been analyzed by RNA-seq to estimate the transcript abundance of each protein-coding gene. The RNA-seq data was then used to classify all genes according to their cell line-specific expression into one of six different categories, defined based on the total set of all TPM values in all analyzed cell lines.
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATIONi
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
The protein browser displays the antigen location on the target protein(s) and the features of the target protein. The tabs at the top of the protein view section can be used to switch between the different splice variants to which an antigen has been mapped.
At the top of the view, the position of the antigen (identified by the corresponding HPA identifier) is shown as a green bar. A yellow triangle on the bar indicates a <100% sequence identity to the protein target.
Under the antigens, the maximum percent sequence identity of the protein to all other proteins from other human genes is displayed, using a sliding window of 10 aa residues (HsID 10) or 50 aa residues (HsID 50) (read more).
If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius (turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.
Low complexity regions are shown in yellow and InterPro regions in green. Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed (read more), and at the bottom of the protein view is the protein scale.
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
P16671 [Direct mapping] Platelet glycoprotein 4 A4D1B1 [Target identity:100%; Query identity:100%] CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
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CD markers Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014)
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001954 [positive regulation of cell-matrix adhesion] GO:0002221 [pattern recognition receptor signaling pathway] GO:0002224 [toll-like receptor signaling pathway] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0002576 [platelet degranulation] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0005041 [low-density lipoprotein receptor activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005794 [Golgi apparatus] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006629 [lipid metabolic process] GO:0006898 [receptor-mediated endocytosis] GO:0006910 [phagocytosis, recognition] GO:0007155 [cell adhesion] GO:0007166 [cell surface receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007263 [nitric oxide mediated signal transduction] GO:0007596 [blood coagulation] GO:0008035 [high-density lipoprotein particle binding] GO:0008289 [lipid binding] GO:0009897 [external side of plasma membrane] GO:0009986 [cell surface] GO:0010629 [negative regulation of gene expression] GO:0010744 [positive regulation of macrophage derived foam cell differentiation] GO:0010886 [positive regulation of cholesterol storage] GO:0016020 [membrane] GO:0019915 [lipid storage] GO:0019934 [cGMP-mediated signaling] GO:0030168 [platelet activation] GO:0030169 [low-density lipoprotein particle binding] GO:0030194 [positive regulation of blood coagulation] GO:0030299 [intestinal cholesterol absorption] GO:0030301 [cholesterol transport] GO:0030666 [endocytic vesicle membrane] GO:0031092 [platelet alpha granule membrane] GO:0031526 [brush border membrane] GO:0032735 [positive regulation of interleukin-12 production] GO:0032755 [positive regulation of interleukin-6 production] GO:0032760 [positive regulation of tumor necrosis factor production] GO:0033993 [response to lipid] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034197 [triglyceride transport] GO:0034381 [plasma lipoprotein particle clearance] GO:0034383 [low-density lipoprotein particle clearance] GO:0035634 [response to stilbenoid] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0042953 [lipoprotein transport] GO:0042992 [negative regulation of transcription factor import into nucleus] GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling] GO:0043277 [apoptotic cell clearance] GO:0043410 [positive regulation of MAPK cascade] GO:0044130 [negative regulation of growth of symbiont in host] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0044539 [long-chain fatty acid import] GO:0045087 [innate immune response] GO:0045121 [membrane raft] GO:0045177 [apical part of cell] GO:0045335 [phagocytic vesicle] GO:0050431 [transforming growth factor beta binding] GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] GO:0050830 [defense response to Gram-positive bacterium] GO:0050892 [intestinal absorption] GO:0050909 [sensory perception of taste] GO:0055096 [low-density lipoprotein particle mediated signaling] GO:0060100 [positive regulation of phagocytosis, engulfment] GO:0060907 [positive regulation of macrophage cytokine production] GO:0070053 [thrombospondin receptor activity] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070508 [cholesterol import] GO:0070542 [response to fatty acid] GO:0070543 [response to linoleic acid] GO:0070892 [lipoteichoic acid receptor activity] GO:0071221 [cellular response to bacterial lipopeptide] GO:0071222 [cellular response to lipopolysaccharide] GO:0071223 [cellular response to lipoteichoic acid] GO:0071447 [cellular response to hydroperoxide] GO:0071813 [lipoprotein particle binding] GO:2000121 [regulation of removal of superoxide radicals] GO:2000334 [positive regulation of blood microparticle formation] GO:2000379 [positive regulation of reactive oxygen species metabolic process] GO:2000505 [regulation of energy homeostasis]
P16671 [Direct mapping] Platelet glycoprotein 4 A4D1B1 [Target identity:100%; Query identity:100%] CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion] GO:0002224 [toll-like receptor signaling pathway] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0002576 [platelet degranulation] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0005041 [low-density lipoprotein receptor activity] GO:0005615 [extracellular space] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006629 [lipid metabolic process] GO:0006898 [receptor-mediated endocytosis] GO:0007155 [cell adhesion] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007263 [nitric oxide mediated signal transduction] GO:0007596 [blood coagulation] GO:0008289 [lipid binding] GO:0009986 [cell surface] GO:0010744 [positive regulation of macrophage derived foam cell differentiation] GO:0016020 [membrane] GO:0019915 [lipid storage] GO:0019934 [cGMP-mediated signaling] GO:0030168 [platelet activation] GO:0030169 [low-density lipoprotein particle binding] GO:0030299 [intestinal cholesterol absorption] GO:0030301 [cholesterol transport] GO:0030666 [endocytic vesicle membrane] GO:0031092 [platelet alpha granule membrane] GO:0031526 [brush border membrane] GO:0033993 [response to lipid] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034197 [triglyceride transport] GO:0034381 [plasma lipoprotein particle clearance] GO:0034383 [low-density lipoprotein particle clearance] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0042953 [lipoprotein transport] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0044539 [long-chain fatty acid import] GO:0045087 [innate immune response] GO:0045335 [phagocytic vesicle] GO:0050431 [transforming growth factor beta binding] GO:0050892 [intestinal absorption] GO:0050909 [sensory perception of taste] GO:0070053 [thrombospondin receptor activity] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070508 [cholesterol import] GO:0070542 [response to fatty acid] GO:0070543 [response to linoleic acid] GO:0071813 [lipoprotein particle binding] GO:2000505 [regulation of energy homeostasis]
P16671 [Direct mapping] Platelet glycoprotein 4 A4D1B1 [Target identity:100%; Query identity:100%] CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion] GO:0002224 [toll-like receptor signaling pathway] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0002576 [platelet degranulation] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0005041 [low-density lipoprotein receptor activity] GO:0005615 [extracellular space] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006629 [lipid metabolic process] GO:0006898 [receptor-mediated endocytosis] GO:0007155 [cell adhesion] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007263 [nitric oxide mediated signal transduction] GO:0007596 [blood coagulation] GO:0008289 [lipid binding] GO:0009986 [cell surface] GO:0010744 [positive regulation of macrophage derived foam cell differentiation] GO:0016020 [membrane] GO:0019915 [lipid storage] GO:0019934 [cGMP-mediated signaling] GO:0030168 [platelet activation] GO:0030169 [low-density lipoprotein particle binding] GO:0030299 [intestinal cholesterol absorption] GO:0030301 [cholesterol transport] GO:0030666 [endocytic vesicle membrane] GO:0031092 [platelet alpha granule membrane] GO:0031526 [brush border membrane] GO:0033993 [response to lipid] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034197 [triglyceride transport] GO:0034381 [plasma lipoprotein particle clearance] GO:0034383 [low-density lipoprotein particle clearance] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0042953 [lipoprotein transport] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0044539 [long-chain fatty acid import] GO:0045087 [innate immune response] GO:0045335 [phagocytic vesicle] GO:0050431 [transforming growth factor beta binding] GO:0050892 [intestinal absorption] GO:0050909 [sensory perception of taste] GO:0070053 [thrombospondin receptor activity] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070508 [cholesterol import] GO:0070542 [response to fatty acid] GO:0070543 [response to linoleic acid] GO:0071813 [lipoprotein particle binding] GO:2000505 [regulation of energy homeostasis]
P16671 [Direct mapping] Platelet glycoprotein 4 A4D1B1 [Target identity:100%; Query identity:100%] CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion] GO:0002224 [toll-like receptor signaling pathway] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0002576 [platelet degranulation] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0005041 [low-density lipoprotein receptor activity] GO:0005615 [extracellular space] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006629 [lipid metabolic process] GO:0006898 [receptor-mediated endocytosis] GO:0007155 [cell adhesion] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007263 [nitric oxide mediated signal transduction] GO:0007596 [blood coagulation] GO:0008289 [lipid binding] GO:0009986 [cell surface] GO:0010744 [positive regulation of macrophage derived foam cell differentiation] GO:0016020 [membrane] GO:0019915 [lipid storage] GO:0019934 [cGMP-mediated signaling] GO:0030168 [platelet activation] GO:0030169 [low-density lipoprotein particle binding] GO:0030299 [intestinal cholesterol absorption] GO:0030301 [cholesterol transport] GO:0030666 [endocytic vesicle membrane] GO:0031092 [platelet alpha granule membrane] GO:0031526 [brush border membrane] GO:0033993 [response to lipid] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034197 [triglyceride transport] GO:0034381 [plasma lipoprotein particle clearance] GO:0034383 [low-density lipoprotein particle clearance] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0042953 [lipoprotein transport] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0044539 [long-chain fatty acid import] GO:0045087 [innate immune response] GO:0045335 [phagocytic vesicle] GO:0050431 [transforming growth factor beta binding] GO:0050892 [intestinal absorption] GO:0050909 [sensory perception of taste] GO:0070053 [thrombospondin receptor activity] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070508 [cholesterol import] GO:0070542 [response to fatty acid] GO:0070543 [response to linoleic acid] GO:0071813 [lipoprotein particle binding] GO:2000505 [regulation of energy homeostasis]
P16671 [Direct mapping] Platelet glycoprotein 4 A4D1B1 [Target identity:100%; Query identity:100%] CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion] GO:0002224 [toll-like receptor signaling pathway] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0002576 [platelet degranulation] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0005041 [low-density lipoprotein receptor activity] GO:0005615 [extracellular space] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006629 [lipid metabolic process] GO:0006898 [receptor-mediated endocytosis] GO:0007155 [cell adhesion] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007263 [nitric oxide mediated signal transduction] GO:0007596 [blood coagulation] GO:0008289 [lipid binding] GO:0009986 [cell surface] GO:0010744 [positive regulation of macrophage derived foam cell differentiation] GO:0016020 [membrane] GO:0019915 [lipid storage] GO:0019934 [cGMP-mediated signaling] GO:0030168 [platelet activation] GO:0030169 [low-density lipoprotein particle binding] GO:0030299 [intestinal cholesterol absorption] GO:0030301 [cholesterol transport] GO:0030666 [endocytic vesicle membrane] GO:0031092 [platelet alpha granule membrane] GO:0031526 [brush border membrane] GO:0033993 [response to lipid] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034197 [triglyceride transport] GO:0034381 [plasma lipoprotein particle clearance] GO:0034383 [low-density lipoprotein particle clearance] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0042953 [lipoprotein transport] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0044539 [long-chain fatty acid import] GO:0045087 [innate immune response] GO:0045335 [phagocytic vesicle] GO:0050431 [transforming growth factor beta binding] GO:0050892 [intestinal absorption] GO:0050909 [sensory perception of taste] GO:0070053 [thrombospondin receptor activity] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070508 [cholesterol import] GO:0070542 [response to fatty acid] GO:0070543 [response to linoleic acid] GO:0071813 [lipoprotein particle binding] GO:2000505 [regulation of energy homeostasis]
