Cell atlas - GPR87 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GPR87

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Lipid droplets
	Mitochondria
	Nucleoplasm

Human cell
	Mitochondria
	Nucleoplasm
	Vesicles

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	GPR87
Gene description	G protein-coupled receptor 87
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria & lipid droplets. In addition localized to the nucleoplasm.
RNA cell category	Cell line enhanced (hTCEpi, A-431, HaCaT)
Protein evidence	Evidence at transcript level
Main location	Localized to the Lipid droplets (approved), Mitochondria (approved)
Additional location	In addition localized to the Nucleoplasm (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA066313
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (hTCEpi, A-431, HaCaT) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria & lipid droplets. In addition localized to the nucleoplasm.

Main location

Lipid droplets (approved), Mitochondria (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA066313	A-431	Nucleoplasm
			Lipid droplets
			Mitochondria	Intensity
	HPA066313	HaCaT	Nucleoplasm
			Lipid droplets
			Mitochondria
	HPA066313	U-2 OS	Nucleoplasm
			Lipid droplets
			Mitochondria	Intensity

GENE INFORMATION
Gene name	GPR87 (HGNC Symbol)
Synonyms	GPR95
Description	G protein-coupled receptor 87 (HGNC Symbol)
Entrez gene summary	This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011]
Chromosome	3
Cytoband	q25.1
Chromosome location (bp)	151294086 - 151316952
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000138271 (version 83.38)
Entrez gene	53836
UniProt	Q9BY21 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BY21
Antibodypedia	GPR87 antibodies

PROTEIN BROWSER

GPR87-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR87-001 ENSP00000260843 ENST00000260843	Q9BY21 [Direct mapping] G-protein coupled receptor 87 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0035589 [G-protein coupled purinergic nucleotide receptor signaling pathway] GO:0045028 [G-protein coupled purinergic nucleotide receptor activity] Show all	358 aa 41.4 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.