Tissue expression of CLEC1A - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CLEC1A
Gene description	C-type lectin domain family 1, member A
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (placenta)
GTEx:	Mixed
FANTOM5:	Expressed in all

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (placenta)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CLEC1A (HGNC Symbol)
Synonyms	CLEC1, MGC34328
Description	C-type lectin domain family 1, member A (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Chromosome	12
Cytoband	p13.2
Chromosome location (bp)	10069554 - 10111627
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000150048 (version 83.38)
Entrez gene	51267
UniProt	Q8NC01 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NC01
Antibodypedia	CLEC1A antibodies

PROTEIN BROWSER

CLEC1A-001	CLEC1A-002	CLEC1A-003	CLEC1A-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLEC1A-001 ENSP00000326407 ENST00000315330	Q8NC01 [Direct mapping] C-type lectin domain family 1 member A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0005622 [intracellular] GO:0005887 [integral component of plasma membrane] GO:0006952 [defense response] GO:0007166 [cell surface receptor signaling pathway] GO:0030246 [carbohydrate binding] Show all	280 aa 32 kDa	No	1
CLEC1A-002 ENSP00000396272 ENST00000414501	F8WCT4 [Direct mapping] C-type lectin domain family 1 member A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	70 aa 7.7 kDa	No	1
CLEC1A-003 ENSP00000415048 ENST00000457018	E9PFB4 [Direct mapping] C-type lectin domain family 1 member A Show all	Predicted intracellular proteins Show all		247 aa 28.4 kDa	No	0
CLEC1A-004 ENSP00000417010 ENST00000420265	E7ESV9 [Direct mapping] C-type lectin domain family 1 member A Show all	Predicted intracellular proteins Show all		188 aa 21.7 kDa	No	0