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RNA tissue category: Group enriched (bone marrow, spleen)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (spleen, lung)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (spleen, heart muscle, lung)
GENE INFORMATION
Gene name
PF4 (HGNC Symbol)
Synonyms
CXCL4, SCYB4
Description
Platelet factor 4 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]