Tissue expression of DCSTAMP - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	DCSTAMP
Gene description	Dendrocyte expressed seven transmembrane protein
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (lung, epididymis)
GTEx:	Group enriched (lung, adipose tissue)
FANTOM5:	Group enriched (adipose tissue, lung)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (lung, epididymis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (lung, adipose tissue)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, lung)

GENE INFORMATION
Gene name	DCSTAMP (HGNC Symbol)
Synonyms	DC-STAMP, FIND, TM7SF4
Description	Dendrocyte expressed seven transmembrane protein (HGNC Symbol)
Entrez gene summary	This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Chromosome	8
Cytoband	q22.3
Chromosome location (bp)	104339087 - 104356689
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164935 (version 83.38)
Entrez gene	81501
UniProt	Q9H295 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H295
Antibodypedia	DCSTAMP antibodies

PROTEIN BROWSER

DCSTAMP-001	DCSTAMP-007	DCSTAMP-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DCSTAMP-001 ENSP00000297581 ENST00000297581	Q9H295 [Direct mapping] Dendritic cell-specific transmembrane protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005887 [integral component of plasma membrane] GO:0009986 [cell surface] GO:0010008 [endosome membrane] GO:0016021 [integral component of membrane] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030308 [negative regulation of cell growth] GO:0030316 [osteoclast differentiation] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0034241 [positive regulation of macrophage fusion] GO:0036006 [cellular response to macrophage colony-stimulating factor stimulus] GO:0043011 [myeloid dendritic cell differentiation] GO:0045657 [positive regulation of monocyte differentiation] GO:0045780 [positive regulation of bone resorption] GO:0061025 [membrane fusion] GO:0071353 [cellular response to interleukin-4] GO:0071356 [cellular response to tumor necrosis factor] GO:0072675 [osteoclast fusion] Show all	470 aa 53.4 kDa	No	5
DCSTAMP-007 ENSP00000428869 ENST00000517991	Q9H295 [Direct mapping] Dendritic cell-specific transmembrane protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005887 [integral component of plasma membrane] GO:0009986 [cell surface] GO:0010008 [endosome membrane] GO:0016021 [integral component of membrane] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030308 [negative regulation of cell growth] GO:0030316 [osteoclast differentiation] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0034241 [positive regulation of macrophage fusion] GO:0036006 [cellular response to macrophage colony-stimulating factor stimulus] GO:0043011 [myeloid dendritic cell differentiation] GO:0045657 [positive regulation of monocyte differentiation] GO:0045780 [positive regulation of bone resorption] GO:0061025 [membrane fusion] GO:0071353 [cellular response to interleukin-4] GO:0071356 [cellular response to tumor necrosis factor] GO:0072675 [osteoclast fusion] Show all	283 aa 31.6 kDa	No	3
DCSTAMP-201 ENSP00000480546 ENST00000622554	Q9H295 [Direct mapping] Dendritic cell-specific transmembrane protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005887 [integral component of plasma membrane] GO:0009986 [cell surface] GO:0010008 [endosome membrane] GO:0016021 [integral component of membrane] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030308 [negative regulation of cell growth] GO:0030316 [osteoclast differentiation] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0034241 [positive regulation of macrophage fusion] GO:0036006 [cellular response to macrophage colony-stimulating factor stimulus] GO:0043011 [myeloid dendritic cell differentiation] GO:0045657 [positive regulation of monocyte differentiation] GO:0045780 [positive regulation of bone resorption] GO:0061025 [membrane fusion] GO:0071353 [cellular response to interleukin-4] GO:0071356 [cellular response to tumor necrosis factor] GO:0072675 [osteoclast fusion] Show all	283 aa 31.6 kDa	No	3