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Most cancer tissues showed moderate to strong cytoplasmic positivity with a granular pattern. Gliomas, renal cell carcinomas along with several liver, skin, colorectal, urothelial and stomach cancers were weakly stained or negative.
GENE INFORMATION
Gene name
SIX2
Synonyms
Description
SIX homeobox 2 (HGNC Symbol)
Entrez gene summary
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. [provided by RefSeq, Dec 2008]