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CLDN20

GENERAL INFORMATION

Gene name

 CLDN20

Gene description

 Claudin 20

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Not detected

Protein evidence

 Evidence at transcript level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected

GENE INFORMATION

Gene name

 CLDN20

Synonyms

Description

 Claudin 20 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010]

Chromosome

 6

Cytoband

 q25.3

Chromosome location (bp)

 155264013 - 155276548

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000171217 (version 83.38)

Entrez gene

 49861

UniProt

 P56880 (UniProt - Evidence at transcript level)

neXtProt

 NX_P56880

Antibodypedia

 CLDN20 antibodies

PROTEIN BROWSER
CLDN20-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CLDN20-001
ENSP00000356133
ENST00000367165
P56880 [Direct mapping]
Claudin-20
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0005198 [structural molecule activity]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0016021 [integral component of membrane]
GO:0016338 [calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules]
GO:0034329 [cell junction assembly]
GO:0042802 [identical protein binding]
GO:0045216 [cell-cell junction organization]
GO:0070830 [bicellular tight junction assembly]
Show all
 219 aa
23.5 kDa 		Yes 3

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.