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Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

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Antibodies

Column

 
 
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BCL2L1
  • TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene namei

Gene name according to HGNC.

BCL2L1

Gene descriptioni

Gene description according to HGNC.

BCL2-like 1

Protein classi

Protein class the gene product belongs to according to selected gene lists. List of protein classes.

Cancer-related genes
Predicted intracellular proteins
Predicted membrane proteins
RAS pathway related proteins
Transporters

Predicted localizationi

Protein localization predicted from several bioinformatic algorithms.

Read more

Intracellular,Membrane

Number of transcriptsi

Number of protein-coding transcribed from this gene as defined by Ensembl.

9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue categoryi

The RNA tissue category is based on mRNA expression levels in the analyzed tissues (RNA assay description). The categories include: tissue enriched, group enriched, tissue enhanced, expressed in all, mixed and not detected. RNA tissue category is calculated separately both for internally generated Human Protein Atlas (HPA) RNA-seq data, as well as RNA-seq data from the Genotype-Tissue Expression (GTEx) project and CAGE data from FANTOM5 project.

Read more

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidencei

Protein evidence scores are generated from several independent sources and are classified as evidence at i) protein level, ii) transcript level, iii) no evidence, or iv) not available.

Evidence at protein level

Protein expressioni

A summary of the overall protein expression pattern across the analyzed tissues. The summary is based on knowledge-based annotation.

"Estimation of protein expression could not be performed. View primary data." is shown for genes analyzed with a knowledge-based approach where available RNA-seq and gene/protein characterization data has been evaluated as not sufficient in combination with immunohistochemistry data to yield a reliable estimation of the protein expression profile.

Read more

Cytoplasmic expression in a few tissues, including bone marrow, lymph node and cells in tubules.

DATA RELIABILITY

Data reliability
descriptioni

Standardized explanatory sentences with additional information required for full understanding of the knowledge-based expression profile.

Antibody staining mainly not consistent with RNA expression data.

Reliability scorei

Reliability score (score description), divided into Supported, Approved, or Uncertain, is based on consistency between the staining pattern of one antibody or several antibodies with RNA-seq data and available gene/protein characterization data.

Read more

Approved based on 1 antibody.
HPA035734
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARYi

Below is an overview of RNA and protein expression data generated in the Human Protein Atlas project. Analyzed tissues are divided into color-coded groups according to which functional features they have in common. For each group, a list of included tissues is accessed by clicking on group name, group symbol, RNA bar, or protein bar. Subsequent selection of a particular tissue in this list links to the image data page. Images of selected tissues give a visual summary of the protein expression profile furthest to the right. The gray human body provides links to a histology dictionary when clicking on any part of the figure.

RNA expression (TPM)i
RNA-seq results generated in HPA are reported as number of transcripts per million (TPM). Each bar represents the highest expression score found in a particular group of tissues. The assay is described more in detail in Assays & Annotation.
Protein expression (score)i
Each bar represents the highest expression score found in a particular group of tissues. Protein expression scores are based on a best estimate of the "true" protein expression from a knowledge-based annotation, described more in detail under Assays & annotation. For genes where more than one antibody has been used, a collective score is set displaying the estimated true protein expression.

Read more
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
N/A
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEWi

Protein expression data is shown for each of the 44 tissues. The color-coding is based on tissues with functional features in common. Mouse-over function shows protein score for analyzed cell types found in a selected tissue. To access image data click on tissue name or bar. Annotation of protein expression is described in detail in Assays & annotation.

For genes with available protein data for which a knowledge-based annotation gave inconclusive results, no protein expression data is displayed in the protein expression data overview, however, all immunohistochemical images are still available and the annotation data can be found under Primary data.

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEWi

RNA expression overview shows RNA-data from three different sources: Internally generated Human Protein Atlas (HPA) RNA-seq data, RNA-seq data from the Genotype-Tissue Expression (GTEx) project and CAGE data from FANTOM5 project. Color-coding is based on tissue groups, each consisting of tissues with functional features in common. To access sample data, click on tissue name or bar.

HPA dataseti

HPA dataset
RNA-seq tissue data is reported as mean TPM (transcripts per million), corresponding to mean values of the different individual samples from each tissue. Color-coding is based on tissue groups, each consisting of tissues with functional features in common. To access sample data, click on tissue name or bar. The RNA-seq assay is described in detail in Assays & Annotation.

RNA tissue category HPA
HPA RNA tissue category (category description) is calculated based on mRNA expression levels across all tissues and include: tissue enriched, group enriched, tissue enhanced, expressed in all, mixed and not detected.
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataseti

GTEx dataset
RNA-seq data are reported as median RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found in Assays & Annotation.

RNA tissue category GTEx
GTEx RNA tissue category (category description) is calculated based on mRNA expression levels across all tissues and include: tissue enriched, group enriched, tissue enhanced, expressed in all, mixed and not detected.
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataseti

FANTOM5 dataset
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found in Assays & Annotation.

RNA tissue category FANTOM5
FANTOM5 RNA tissue category (category description) is calculated based on gene expression levels across all tissues and include: tissue enriched, group enriched, tissue enhanced, expressed in all, mixed and not detected.
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Gene name

BCL2L1 (HGNC Symbol)

Synonyms

Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52

Description

BCL2-like 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q11.21

Chromosome location (bp)

31664452 - 31723989

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171552 (version 83.38)

Entrez gene

598

UniProt

Q07817 (UniProt - Evidence at protein level)

neXtProt

NX_Q07817

Antibodypedia

BCL2L1 antibodies

PROTEIN BROWSERi

The protein browser displays the antigen location on the target protein(s) and the features of the target protein. The tabs at the top of the protein view section can be used to switch between the different splice variants to which an antigen has been mapped.

At the top of the view, the position of the antigen (identified by the corresponding HPA identifier) is shown as a green bar. A yellow triangle on the bar indicates a <100% sequence identity to the protein target.

Under the antigens, the maximum percent sequence identity of the protein to all other proteins from other human genes is displayed, using a sliding window of 10 aa residues (HsID 10) or 50 aa residues (HsID 50) (read more).

If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius (turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.

Low complexity regions are shown in yellow and InterPro regions in green. Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed (read more), and at the bottom of the protein view is the protein scale.

BCL2L1-001
BCL2L1-002
BCL2L1-003
BCL2L1-004
BCL2L1-005
BCL2L1-006
BCL2L1-007
BCL2L1-008
BCL2L1-009

PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCL2L1-001
ENSP00000365230
ENST00000376062
Q07817 [Direct mapping]
Bcl-2-like protein 1
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0001836 [release of cytochrome c from mitochondria]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005743 [mitochondrial inner membrane]
GO:0005759 [mitochondrial matrix]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0006897 [endocytosis]
GO:0006915 [apoptotic process]
GO:0007093 [mitotic cell cycle checkpoint]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0008637 [apoptotic mitochondrial changes]
GO:0010507 [negative regulation of autophagy]
GO:0012501 [programmed cell death]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0019050 [suppression by virus of host apoptotic process]
GO:0019901 [protein kinase binding]
GO:0030054 [cell junction]
GO:0030672 [synaptic vesicle membrane]
GO:0031965 [nuclear membrane]
GO:0034097 [response to cytokine]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0045087 [innate immune response]
GO:0046902 [regulation of mitochondrial membrane permeability]
GO:0046982 [protein heterodimerization activity]
GO:0051434 [BH3 domain binding]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090201 [negative regulation of release of cytochrome c from mitochondria]
GO:0097136 [Bcl-2 family protein complex]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
GO:0097193 [intrinsic apoptotic signaling pathway]
GO:1900118 [negative regulation of execution phase of apoptosis]
GO:1902230 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage]
GO:2000811 [negative regulation of anoikis]
GO:2001240 [negative regulation of extrinsic apoptotic signaling pathway in absence of ligand]
GO:2001243 [negative regulation of intrinsic apoptotic signaling pathway]
GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]
Show all
233 aa
26 kDa
No 2
BCL2L1-002
ENSP00000365223
ENST00000376055
Q07817 [Direct mapping]
Bcl-2-like protein 1
Q5TE63 [Target identity:100%; Query identity:100%]
BCL2-like 1, isoform CRA_c; cDNA FLJ77105, highly similar to Homo sapiens BCL2-like 1 (BCL2L1), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0001836 [release of cytochrome c from mitochondria]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005743 [mitochondrial inner membrane]
GO:0005759 [mitochondrial matrix]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0006897 [endocytosis]
GO:0006915 [apoptotic process]
GO:0007093 [mitotic cell cycle checkpoint]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0008637 [apoptotic mitochondrial changes]
GO:0010507 [negative regulation of autophagy]
GO:0012501 [programmed cell death]
GO:0016021 [integral component of membrane]
GO:0019050 [suppression by virus of host apoptotic process]
GO:0019901 [protein kinase binding]
GO:0030054 [cell junction]
GO:0030672 [synaptic vesicle membrane]
GO:0031965 [nuclear membrane]
GO:0034097 [response to cytokine]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0045087 [innate immune response]
GO:0046902 [regulation of mitochondrial membrane permeability]
GO:0046982 [protein heterodimerization activity]
GO:0051434 [BH3 domain binding]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090201 [negative regulation of release of cytochrome c from mitochondria]
GO:0097136 [Bcl-2 family protein complex]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
GO:0097193 [intrinsic apoptotic signaling pathway]
GO:1900118 [negative regulation of execution phase of apoptosis]
GO:1902230 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage]
GO:2000811 [negative regulation of anoikis]
GO:2001240 [negative regulation of extrinsic apoptotic signaling pathway in absence of ligand]
GO:2001243 [negative regulation of intrinsic apoptotic signaling pathway]
GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]
Show all
170 aa
18.9 kDa
No 1
BCL2L1-003
ENSP00000406203
ENST00000450273
Q5TE64 [Direct mapping]
Bcl-2-like protein 1
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005739 [mitochondrion]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0016020 [membrane]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
Show all
205 aa
22.9 kDa
No 0
BCL2L1-004
ENSP00000302564
ENST00000307677
Q07817 [Direct mapping]
Bcl-2-like protein 1
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
RAS pathway related proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0001541 [ovarian follicle development]
GO:0001701 [in utero embryonic development]
GO:0001836 [release of cytochrome c from mitochondria]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005743 [mitochondrial inner membrane]
GO:0005759 [mitochondrial matrix]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0006897 [endocytosis]
GO:0006915 [apoptotic process]
GO:0007093 [mitotic cell cycle checkpoint]
GO:0007281 [germ cell development]
GO:0007283 [spermatogenesis]
GO:0008283 [cell proliferation]
GO:0008284 [positive regulation of cell proliferation]
GO:0008584 [male gonad development]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0008637 [apoptotic mitochondrial changes]
GO:0009314 [response to radiation]
GO:0009566 [fertilization]
GO:0009615 [response to virus]
GO:0010507 [negative regulation of autophagy]
GO:0012501 [programmed cell death]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0019050 [suppression by virus of host apoptotic process]
GO:0019901 [protein kinase binding]
GO:0030054 [cell junction]
GO:0030672 [synaptic vesicle membrane]
GO:0031965 [nuclear membrane]
GO:0031966 [mitochondrial membrane]
GO:0034097 [response to cytokine]
GO:0035872 [nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway]
GO:0040007 [growth]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045087 [innate immune response]
GO:0046898 [response to cycloheximide]
GO:0046902 [regulation of mitochondrial membrane permeability]
GO:0046982 [protein heterodimerization activity]
GO:0051402 [neuron apoptotic process]
GO:0051434 [BH3 domain binding]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0060154 [cellular process regulating host cell cycle in response to virus]
GO:0070584 [mitochondrion morphogenesis]
GO:0071230 [cellular response to amino acid stimulus]
GO:0071312 [cellular response to alkaloid]
GO:0071480 [cellular response to gamma radiation]
GO:0071839 [apoptotic process in bone marrow]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090201 [negative regulation of release of cytochrome c from mitochondria]
GO:0097136 [Bcl-2 family protein complex]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
GO:0097193 [intrinsic apoptotic signaling pathway]
GO:0097284 [hepatocyte apoptotic process]
GO:1900118 [negative regulation of execution phase of apoptosis]
GO:1902230 [negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage]
GO:2000811 [negative regulation of anoikis]
GO:2001240 [negative regulation of extrinsic apoptotic signaling pathway in absence of ligand]
GO:2001243 [negative regulation of intrinsic apoptotic signaling pathway]
GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway]
Show all
233 aa
26 kDa
No 2
BCL2L1-005
ENSP00000389688
ENST00000439267
Q5QP56 [Direct mapping]
Bcl-2-like protein 1
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005739 [mitochondrion]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
Show all
181 aa
20.2 kDa
No 0
BCL2L1-006
ENSP00000390760
ENST00000420488
Q9H1R6 [Direct mapping]
Bcl-2-like protein 1
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005739 [mitochondrion]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
Show all
188 aa
21 kDa
No 0
BCL2L1-007
ENSP00000395545
ENST00000456404
Q9H1R6 [Direct mapping]
Bcl-2-like protein 1
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005739 [mitochondrion]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
Show all
188 aa
21 kDa
No 0
BCL2L1-008
ENSP00000411252
ENST00000422920
Q9H1R6 [Direct mapping]
Bcl-2-like protein 1
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005739 [mitochondrion]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
Show all
188 aa
21 kDa
No 0
BCL2L1-009
ENSP00000401173
ENST00000434194
Q5QP59 [Direct mapping]
Bcl-2-like protein 1
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0046982 [protein heterodimerization activity]
GO:0097192 [extrinsic apoptotic signaling pathway in absence of ligand]
Show all
48 aa
5.5 kDa
No 0

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