Tissue expression of CHST6 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CHST6
Gene description	Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
Protein class	Disease related genes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cervix, uterine, small intestine, duodenum)
GTEx:	Mixed
FANTOM5:	Tissue enhanced (cerebellum, hippocampus)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cervix, uterine, small intestine, duodenum)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum, hippocampus)

GENE INFORMATION
Gene name	CHST6 (HGNC Symbol)
Synonyms	MCDC1
Description	Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an enzyme that catalyzes the transfer of a sulfate group to the GlcNAc residues of keratan. Keratan sulfate helps maintain corneal transparency. Defects in this gene are a cause of macular corneal dystrophy (MCD). [provided by RefSeq, Jan 2010]
Chromosome	16
Cytoband	q23.1
Chromosome location (bp)	75472052 - 75495384
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183196 (version 83.38)
Entrez gene	4166
UniProt	Q9GZX3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9GZX3
Antibodypedia	CHST6 antibodies

PROTEIN BROWSER

CHST6-001	CHST6-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CHST6-001 ENSP00000375079 ENST00000390664	Q9GZX3 [Direct mapping] Carbohydrate sulfotransferase 6 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Show all	GO:0000139 [Golgi membrane] GO:0001517 [N-acetylglucosamine 6-O-sulfotransferase activity] GO:0005794 [Golgi apparatus] GO:0005975 [carbohydrate metabolic process] GO:0006044 [N-acetylglucosamine metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0008146 [sulfotransferase activity] GO:0016021 [integral component of membrane] GO:0018146 [keratan sulfate biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0042339 [keratan sulfate metabolic process] GO:0044281 [small molecule metabolic process] Show all	395 aa 44.1 kDa	Yes	0
CHST6-003 ENSP00000328983 ENST00000332272	Q9GZX3 [Direct mapping] Carbohydrate sulfotransferase 6 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Show all	GO:0000139 [Golgi membrane] GO:0001517 [N-acetylglucosamine 6-O-sulfotransferase activity] GO:0005794 [Golgi apparatus] GO:0005975 [carbohydrate metabolic process] GO:0006044 [N-acetylglucosamine metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0008146 [sulfotransferase activity] GO:0016021 [integral component of membrane] GO:0018146 [keratan sulfate biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0042339 [keratan sulfate metabolic process] GO:0044281 [small molecule metabolic process] Show all	395 aa 44.1 kDa	Yes	0