Cell atlas - GPR89B - The Human Protein Atlas

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GPR89B

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Endoplasmic reticulum

Human cell
	Endoplasmic Reticulum

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GENERAL INFORMATION
Gene name	GPR89B
Gene description	G protein-coupled receptor 89B
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the endoplasmic reticulum. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Endoplasmic reticulum (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA076096
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the endoplasmic reticulum. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Endoplasmic reticulum (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA076096	MCF7	Endoplasmic reticulum
	HPA076096	SiHa	Endoplasmic reticulum
	HPA076096	U-2 OS	Endoplasmic reticulum

GENE INFORMATION
Gene name	GPR89B (HGNC Symbol)
Synonyms	GPR89, GPR89C, SH120
Description	G protein-coupled receptor 89B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.2
Chromosome location (bp)	147928393 - 147993521
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188092 (version 83.38)
Entrez gene	51463
UniProt	P0CG08 (UniProt - Evidence at protein level)
neXtProt	NX_P0CG08
Antibodypedia	GPR89B antibodies

PROTEIN BROWSER

GPR89B-001	GPR89B-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR89B-001 ENSP00000358233 ENST00000314163	P0CG08 [Direct mapping] Golgi pH regulator B X5D7G6 [Target identity:100%; Query identity:100%] G protein-coupled receptor 89A isoform C; G protein-coupled receptor 89B isoform C Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005244 [voltage-gated ion channel activity] GO:0006811 [ion transport] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034765 [regulation of ion transmembrane transport] Show all	455 aa 52.9 kDa	No	9
GPR89B-008 ENSP00000475253 ENST00000468618	U3KPV2 [Direct mapping] Golgi pH regulator B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	216 aa 25.1 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.