THE HUMAN PROTEIN ATLAS BLOG

Proteomics methods promote understanding autoimmunity in neurodegenerative disorders

2017-10-09
Affinity proteomics blood samples Malaria Multiple Sclerosis narcolepsy Neurodegenerative disorders Plasma Plasma Profilling psychosis

Arash Zandian's doctoral thesis defense at SciLifeLab, KTH

The last decades of technical development and availability of protein and peptide microarrays have enabled large-scale profiling of antibodies and precise determination of their specificities through epitope mapping. This has enabled characterization of the human immune response and the produced antibodies. Beside exploring the auto-antibody repertoire, this approach also identifies key autoantigens targeted by the antibodies in e.g. neurodegenerative disorders...Read more


World Malaria Day April 25

2017-04-25
Malaria Tissue Atlas

SLC4A1 in kidney.

This blog post is in honor of World Malaria Day

When infected mosquitos bite people they transmit parasites that causes malaria. Symptoms of malaria include fever and flu-like illness, and if left untreated the illness will cause anemia (loss of red blood cells) and eventually death.

According to WHO, malaria caused 429 000 deaths in 2015, and 70% of the deaths are children under the age of 5. Luckily, mortality rates are falling, and since 2010 the mortality has dropped with almost 1/3. Early diagnosis and treatment of malaria reduces deaths and prevents transmission. There are antimalaria drugs available, but currently, there is no availabe malaria vaccine...Read more


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