THE HUMAN PROTEIN ATLAS BLOG

TACO1 an ubiquitous protein governing expression of the mitochondrial genome

2017-04-21
Cell Atlas cells Image of the week Immunofluorescence microscopy Mitochondria Mitochondrial disorders

Antibody HPA021643 in U-2 OS recognizing TACO1 in mitochondria.

Mitochondria harbors an own genome that renders key proteins involved in production of energy through oxidation of various substrates. Majority of the disorders associated with mitochondrial function are caused by impaired expression of the proteins encoded in the mitochondrial genome. One of these proteins is the translational activator of cytochrome c oxidase 1 (TACO1).

Experimental results reveal that TACO1 is expressed in all tissues within the human body. The protein is detected mainly in the cytoplasm and more precise inside mitochondria. Explore expression and subcellular localization of TACO1 in the Cell Atlas...Read more


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