THE HUMAN PROTEIN ATLAS BLOG

Proteomics methods promote understanding autoimmunity in neurodegenerative disorders

2017-10-09
Affinity proteomics blood samples Malaria Multiple Sclerosis narcolepsy Neurodegenerative disorders Plasma Plasma Profilling psychosis

Arash Zandian's doctoral thesis defense at SciLifeLab, KTH

The last decades of technical development and availability of protein and peptide microarrays have enabled large-scale profiling of antibodies and precise determination of their specificities through epitope mapping. This has enabled characterization of the human immune response and the produced antibodies. Beside exploring the auto-antibody repertoire, this approach also identifies key autoantigens targeted by the antibodies in e.g. neurodegenerative disorders...Read more


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