THE HUMAN PROTEIN ATLAS BLOG

TNFRSF14 in Rods and Rings

2017-03-10
Rods and Rings

Figure 1. Co-staining of TNFRSF14 (green) with a Rods & Rings marker protein (red) and DAPI (blue) in U-2 OS cells. Overlapping regions appear yellow.

This week we highlight a new structure in the Cell Atlas available in version 16 thanks to the annotations done by citizen scientists in Project Discovery, a mini game within EVE Online. Rods & Rings.

As the name describes, these unique structures that form large rod and ring type aggregates in the cytoplasm that look a bit like sprinkles. Little is known about this structure and the proteins that are involved in it. In fact, it wasn't until 2011 when the term "Rods & Rings" was coined (Seeling HP et al. 2011,Carcamo WC et al. 2011)...Read more


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