THE HUMAN PROTEIN ATLAS BLOG

Human Protein Atlas presentations at the 16th HUPO World Congress

2017-09-14
Affinity proteomics Cell Atlas Conference Human Protein Atlas Immunofluorescence microscopy Immunohistochemistry Sub-cellular structures Tissue Atlas

Next week on the 17th to 21th of September, the human proteome organization (HUPO), is hosting the 16th HUPO World Congress in Dublin, Ireland. Several Human Protein Atlas-associated researchers will attend the meeting and represent the project in various sessions, including plenary and invited lectures, oral presentations and poster sessions.

HUPO is an international scientific organization representing and promoting proteomics through international cooperation and collaborations by fostering the development of new technologies, techniques and training...Read more


Citrate synthase and mitochondrial disease

2016-09-23
Cell Atlas cells Immunofluorescence microscopy Sub-cellular structures

Figure 1. Staining of CS (green) with DAPI (blue) and microtubules (red) in U2 OS cells.

Mitochondria are responsible for the energy production in our cells. The most interesting thing about mitochondria is that they have their own DNA which means some proteins in the mitochondria come from nuclear DNA and some from mitochondrial DNA. In a previous image of the week we highlighted TOMM5, a protein responsible for transport of nuclear encoded mitochondrial proteins into the mitochondria.

In this week's image of the week we take a look at citrate synthase (CS), a nuclear encoded mitochondrial protein that is a key enzyme for the citric acid cycle of the cell (TCA cycle), also known as the Krebs cycle...Read more


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