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The cancer tissue atlas contains gene expression data based on protein expression patterns in 216 different cancer samples representing the 20 most common forms of human cancer. Protein expression data is derived from antibody-based protein profiling using immunohistochemistry. The data is presented as pathology-based annotation of protein expression levels. All underlying images of immunohistochemistry stained cancer tissues are available as high-resolution images in the cancer tissue atlas together with basic information regarding age, gender and tumor phenotype.
The protein data includes protein expression levels corresponding to 15297 genes for which there are available antibodies.
More detailed information is available on the Cancer Proteome pages and About sections.
Example proteins in the cancer atlas
EGFR
Epidermal growth factor receptor.
Selective membranous expression in a subset of tumors such as malignant glioma.
Melan-A
MLANA.
Selective cytoplasmic expression in melanomas. All other malignant tissues were negative.
CDK1
Cyclin-dependent kinase 1.
Distinct cytoplasmic and nuclear expression in a subset of tumor cells in most malignant tissues.
SEARCHi
The search function can be used for free text search (type anything in the search field), or for more complex queries using "Fields" (see examples).
The free text search will scan for complete and partial matches to gene names, gene synonyms, gene descriptions, external (UniProt, Ensembl, NCBI Entrez Gene) gene and protein identifiers, protein classes, Gene Ontology identifiers and descriptions, antibody identifiers and image annotations. The free text query word needs to be at least three characters long.
