Focal adhesion sites

Focal adhesions directly interact with the actin filaments and are necessary for the attachment of the cell to the extracellular matrix. They are also involved in cell motility and migration.

Immunofluorescent staining

Focal adhesions are localized adjacent to the plasma membrane and can be found either just under the cell or at the edge of the plasma membrane, where the cell is attached to the surface.

Read more about the proteome of the actin filaments.