Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS TPM TPM max in non-specific HTR1A 5-HT1A, ADRB2RL1, ADRBRL1 ENSG00000178394 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 5 63960356-63962507 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA018073 Uncertain Group enriched 10 cerebral cortex: 1.9;ovary: 3.9 testis: 0.2 HTR1B 5-HT1B, 5-HT1DB, HTR1D2, S12 ENSG00000135312 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 6 77462205-77463464 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA028808 Approved Uncertain Plasma membrane Tissue enhanced 0 placenta: 13.7;stomach: 5.8 cerebral cortex: 2.8 HTR1D 5-HT1D, HT1DA, HTRL, RDC4 ENSG00000179546 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1 23191895-23194729 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Group enriched 8 duodenum: 9.7;gallbladder: 2.5;small intestine: 9.3 fallopian tube: 0.8 HTR1E 5-HT1E ENSG00000168830 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 6 86937306-87016683 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA004931 Approved Tissue enhanced 0 endometrium: 2.4;ovary: 4.9 cerebral cortex: 1.9 HTR1F 5-HT1F, HTR1EL ENSG00000179097 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 3 87990696-87993835 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA005555 Uncertain Tissue enhanced 0 placenta: 2.7 cerebral cortex: 1.0 HTR2A 5-HT2A, HTR2 ENSG00000102468 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13 46831550-46897076 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014011 Supported Tissue enriched 8 cerebral cortex: 32.3 smooth muscle: 3.8 HTR2B 5-HT(2B), 5-HT2B ENSG00000135914 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2 231108230-231125118 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level CAB011448, HPA012867, HPA063658 Approved Approved Nucleoplasm Tissue enhanced 0 cervix, uterine: 31.1;endometrium: 30.0;smooth muscle: 23.0 adrenal gland: 19.1 HTR2C 5-HT2C, 5HTR2C, HTR1C ENSG00000147246 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled X 114584078-114910061 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Tissue enriched 5 cerebral cortex: 3.1 cervix: 0.5 HTR4 5-HT4 ENSG00000164270 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5 148451032-148677235 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA040591 Approved Tissue enhanced 0 duodenum: 5.0;small intestine: 10.2 heart muscle: 3.5 HTR5A 5-HT5A ENSG00000157219 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 7 155070324-155085749 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level CAB017467 Approved Tissue enriched 11 cerebral cortex: 8.6 testis: 0.7 HTR6 5-HT6, 5-HT6R ENSG00000158748 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1 19665287-19679562 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Not detected cerebral cortex: 0.8 HTR7 5-HT7 ENSG00000148680 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 10 90740823-90857698 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level Evidence at protein level Evidence at protein level CAB022708 Uncertain Supported Nuclear speckles
Plasma membrane
Cytosol Group enriched 8 parathyroid gland: 43.9;testis: 16.0 urinary bladder: 3.9