Expression of BACH2 in cancer - Summary

CANCER ATLAS

Gene description

BTB and CNC homology 1, basic leucine zipper transcription factor 2

Protein class

Plasma proteins, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA051384

GENE INFORMATION
Gene name	BACH2 (HGNC Symbol)
Synonyms	BTBD25
Description	BTB and CNC homology 1, basic leucine zipper transcription factor 2 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q15
Chromosome location (bp)	89926529 - 90296908
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112182 (version 83.38)
Entrez gene	60468
UniProt	Q9BYV9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BYV9
Antibodypedia	BACH2 antibodies

PROTEIN BROWSER

BACH2-002	BACH2-003	BACH2-005	BACH2-007	BACH2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BACH2-002 ENSP00000384145 ENST00000406998	Q7Z6Q0 [Direct mapping] Transcription regulator protein BACH2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	81 aa 9.3 kDa	No	0
BACH2-003 ENSP00000257749 ENST00000257749	Q9BYV9 [Direct mapping] Transcription regulator protein BACH2 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0001206 [transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0016567 [protein ubiquitination] GO:0031463 [Cul3-RING ubiquitin ligase complex] GO:0043565 [sequence-specific DNA binding] Show all	841 aa 92.5 kDa	No	0
BACH2-005 ENSP00000345642 ENST00000343122	Q9BYV9 [Direct mapping] Transcription regulator protein BACH2 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Basic domains Show all	GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0016567 [protein ubiquitination] GO:0031463 [Cul3-RING ubiquitin ligase complex] GO:0043565 [sequence-specific DNA binding] Show all	841 aa 92.5 kDa	No	0
BACH2-007 ENSP00000397668 ENST00000453877	Q7Z6Q0 [Direct mapping] Transcription regulator protein BACH2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	81 aa 9.3 kDa	No	0
BACH2-201 ENSP00000437473 ENST00000537989	Q9BYV9 [Direct mapping] Transcription regulator protein BACH2 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Show all	GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0016567 [protein ubiquitination] GO:0031463 [Cul3-RING ubiquitin ligase complex] GO:0043565 [sequence-specific DNA binding] Show all	841 aa 92.5 kDa	No	0