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Weak to moderate cytoplasmic positivity was observed in a majority of cancers. Lymphomas, skin and cervical cancers were generally negative in several cases.
A majority of cancer cells were either negative or displayed weak cytoplasmic staining. Cases of pancreatic and gastric cancers showed moderate to strong cytoplasmic and/or membrane immunoreactivity.
GENE INFORMATION
Gene name
EFR3A (HGNC Symbol)
Synonyms
KIAA0143
Description
EFR3 homolog A (HGNC Symbol)
Entrez gene summary
This gene encodes a membrane protein. Studies with orthologous gene in mouse show that it is differentially expressed in the auditory brainstem neurons of mice with hearing deficit, compared to mice with normal hearing ability, suggesting a role for this gene in hearing. [provided by RefSeq, Jan 2011]
MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
