Cell atlas - EFR3A - The Human Protein Atlas

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EFR3A

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TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	EFR3A
Gene description	EFR3 homolog A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (supported), Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA023402
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane & cytosol.

Main location

Plasma membrane (supported), Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA023402	A-431	No staining
	HPA023402	U-2 OS	Plasma membrane
	HPA023402	U-2 OS	Cytosol
	HPA023402	U-251 MG	No staining

GENE INFORMATION
Gene name	EFR3A (HGNC Symbol)
Synonyms	KIAA0143
Description	EFR3 homolog A (HGNC Symbol)
Entrez gene summary	This gene encodes a membrane protein. Studies with orthologous gene in mouse show that it is differentially expressed in the auditory brainstem neurons of mice with hearing deficit, compared to mice with normal hearing ability, suggesting a role for this gene in hearing. [provided by RefSeq, Jan 2011]
Chromosome	8
Cytoband	q24.22
Chromosome location (bp)	131904088 - 132013642
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132294 (version 83.38)
Entrez gene	23167
UniProt	Q14156 (UniProt - Evidence at protein level)
neXtProt	NX_Q14156
Antibodypedia	EFR3A antibodies

PROTEIN BROWSER

EFR3A-001	EFR3A-002	EFR3A-003	EFR3A-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EFR3A-001 ENSP00000254624 ENST00000254624	Q14156 [Direct mapping] Protein EFR3 homolog A Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0070062 [extracellular exosome] Show all	821 aa 92.9 kDa	No	0
EFR3A-002 ENSP00000428086 ENST00000519656	Q14156 [Direct mapping] Protein EFR3 homolog A Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005886 [plasma membrane] GO:0070062 [extracellular exosome] Show all	785 aa 88.8 kDa	No	0
EFR3A-003 ENSP00000430512 ENST00000522709	E5RJS1 [Direct mapping] Protein EFR3 homolog A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	133 aa 15.2 kDa	No	0
EFR3A-004 ENSP00000428844 ENST00000520362	E5RFJ2 [Direct mapping] Protein EFR3 homolog A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		13 aa 1.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.