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Most malignant tissues were weakly stained or negative. Malignant gliomas displayed strong immunoreactivity while the testicular tumors mainly showed moderate positivity.
GENE INFORMATION
Gene name
PCDH10 (HGNC Symbol)
Synonyms
KIAA1400, OL-PCDH
Description
Protocadherin 10 (HGNC Symbol)
Entrez gene summary
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]