Tissue expression of ERP27 - Summary - The Human Protein Atlas

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ERP27

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ERP27
Gene description	Endoplasmic reticulum protein 27
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (pancreas, fallopian tube)
GTEx:	Tissue enriched (pancreas)
FANTOM5:	Tissue enhanced (thyroid gland)

Protein evidence

Evidence at protein level

Protein expression

Selective expression of exocrine glandular cells in pancreas.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA039636 , HPA052851
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

N/A

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (pancreas, fallopian tube)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (pancreas)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)

GENE INFORMATION
Gene name	ERP27 (HGNC Symbol)
Synonyms	C12orf46, ERp27, FLJ32115, PDIA8
Description	Endoplasmic reticulum protein 27 (HGNC Symbol)
Entrez gene summary	ERP27 is a noncatalytic member of the protein disulfide isomerase (PDI; see MIM 608012) family of endoplasmic reticulum (ER) proteins (Alanen et al., 2006 [PubMed 16940051]).[supplied by OMIM, Mar 2008]
Chromosome	12
Cytoband	p12.3
Chromosome location (bp)	14914035 - 14939082
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139055 (version 83.38)
Entrez gene	121506
UniProt	Q96DN0 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DN0
Antibodypedia	ERP27 antibodies

PROTEIN BROWSER

ERP27-001	ERP27-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ERP27-001 ENSP00000266397 ENST00000266397	Q96DN0 [Direct mapping] Endoplasmic reticulum resident protein 27 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005788 [endoplasmic reticulum lumen] Show all	273 aa 30.5 kDa	Yes	0
ERP27-002 ENSP00000440573 ENST00000540097	F5GYS6 [Direct mapping] Endoplasmic reticulum resident protein 27 Show all	Predicted intracellular proteins Show all		172 aa 19.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.