Expression of FBXO38 in cancer - Summary

CANCER ATLAS

Gene description

F-box protein 38

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA034821

GENE INFORMATION
Gene name	FBXO38 (HGNC Symbol)
Synonyms	Fbx38, FLJ13962, MOKA, SP329
Description	F-box protein 38 (HGNC Symbol)
Entrez gene summary	This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Chromosome	5
Cytoband	q32
Chromosome location (bp)	148383935 - 148442836
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145868 (version 83.38)
Entrez gene	81545
UniProt	Q6PIJ6 (UniProt - Evidence at protein level)
neXtProt	NX_Q6PIJ6
Antibodypedia	FBXO38 antibodies

PROTEIN BROWSER

FBXO38-001	FBXO38-002	FBXO38-003	FBXO38-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FBXO38-001 ENSP00000377895 ENST00000394370	Q6PIJ6 [Direct mapping] F-box only protein 38 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] Show all	1113 aa 126 kDa	No	0
FBXO38-002 ENSP00000342023 ENST00000340253	Q6PIJ6 [Direct mapping] F-box only protein 38 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] Show all	1188 aa 133.9 kDa	No	0
FBXO38-003 ENSP00000426410 ENST00000513826	Q6PIJ6 [Direct mapping] F-box only protein 38 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] Show all	943 aa 107.7 kDa	No	0
FBXO38-201 ENSP00000296701 ENST00000296701	Q6PIJ6 [Direct mapping] F-box only protein 38 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] Show all	943 aa 107.7 kDa	No	0