Expression of ANO4 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Anoctamin 4

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Testis cancer

STAINING SUMMARY

HPA053412

GENE INFORMATION
Gene name	ANO4 (HGNC Symbol)
Synonyms	FLJ34221, FLJ34272, FLJ35277, TMEM16D
Description	Anoctamin 4 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q23.1
Chromosome location (bp)	100717526 - 101128641
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000151572 (version 83.38)
Entrez gene	121601
UniProt	Q32M45 (UniProt - Evidence at transcript level)
neXtProt	NX_Q32M45
Antibodypedia	ANO4 antibodies

PROTEIN BROWSER

ANO4-001	ANO4-002	ANO4-004	ANO4-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANO4-001 ENSP00000376705 ENST00000392979	Q32M45 [Direct mapping] Anoctamin-4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0005229 [intracellular calcium activated chloride channel activity] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0006869 [lipid transport] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:1902476 [chloride transmembrane transport] Show all	920 aa 107.6 kDa	No	9
ANO4-002 ENSP00000376703 ENST00000392977	Q32M45 [Direct mapping] Anoctamin-4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0005229 [intracellular calcium activated chloride channel activity] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0006869 [lipid transport] GO:0016021 [integral component of membrane] GO:0017128 [phospholipid scramblase activity] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0061589 [calcium activated phosphatidylserine scrambling] GO:0061590 [calcium activated phosphatidylcholine scrambling] GO:0061591 [calcium activated galactosylceramide scrambling] GO:1902476 [chloride transmembrane transport] Show all	955 aa 111.5 kDa	No	9
ANO4-004 ENSP00000450192 ENST00000550015	Q32M45 [Direct mapping] Anoctamin-4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005229 [intracellular calcium activated chloride channel activity] GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006821 [chloride transport] GO:0006869 [lipid transport] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:1902476 [chloride transmembrane transport] Show all	475 aa 55.7 kDa	No	7
ANO4-006 ENSP00000447867 ENST00000546991	F8VUH1 [Direct mapping] Anoctamin-4 Show all	Predicted intracellular proteins Show all		11 aa 1.1 kDa	No	0