Tissue expression of FAIM - Summary - The Human Protein Atlas

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FAIM

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	FAIM
Gene description	Fas apoptotic inhibitory molecule
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and nuclear expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA042440 , HPA052209
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	FAIM (HGNC Symbol)
Synonyms	FAIM1, FLJ10582
Description	Fas apoptotic inhibitory molecule (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Chromosome	3
Cytoband	q22.3
Chromosome location (bp)	138608606 - 138633376
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158234 (version 83.38)
Entrez gene	55179
UniProt	Q9NVQ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NVQ4
Antibodypedia	FAIM antibodies

PROTEIN BROWSER

FAIM-001	FAIM-002	FAIM-003	FAIM-004	FAIM-008	FAIM-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAIM-001 ENSP00000342805 ENST00000338446	Q9NVQ4 [Direct mapping] Fas apoptotic inhibitory molecule 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0043066 [negative regulation of apoptotic process] GO:1902042 [negative regulation of extrinsic apoptotic signaling pathway via death domain receptors] Show all	213 aa 24 kDa	No	0
FAIM-002 ENSP00000376754 ENST00000393034	Q9NVQ4 [Direct mapping] Fas apoptotic inhibitory molecule 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0043066 [negative regulation of apoptotic process] Show all	179 aa 20.2 kDa	No	0
FAIM-003 ENSP00000376755 ENST00000393035	Q9NVQ4 [Direct mapping] Fas apoptotic inhibitory molecule 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0043066 [negative regulation of apoptotic process] Show all	179 aa 20.2 kDa	No	0
FAIM-004 ENSP00000353775 ENST00000360570	Q9NVQ4 [Direct mapping] Fas apoptotic inhibitory molecule 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0043066 [negative regulation of apoptotic process] Show all	201 aa 22.6 kDa	No	0
FAIM-008 ENSP00000417642 ENST00000464668	Q9NVQ4 [Direct mapping] Fas apoptotic inhibitory molecule 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0043066 [negative regulation of apoptotic process] Show all	179 aa 20.2 kDa	No	0
FAIM-009 ENSP00000420543 ENST00000479848	C9JDZ2 [Direct mapping] Fas apoptotic inhibitory molecule 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0043066 [negative regulation of apoptotic process] Show all	128 aa 14.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.