Expression of ADGRG5 in cancer - Summary

CANCER ATLAS

Gene description

Adhesion G protein-coupled receptor G5

Protein class

G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA007133

GENE INFORMATION
Gene name	ADGRG5 (HGNC Symbol)
Synonyms	GPR114, PGR27
Description	Adhesion G protein-coupled receptor G5 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q21
Chromosome location (bp)	57542421 - 57591681
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159618 (version 83.38)
Entrez gene	221188
UniProt	Q8IZF4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IZF4
Antibodypedia	ADGRG5 antibodies

PROTEIN BROWSER

ADGRG5-001	ADGRG5-006	ADGRG5-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADGRG5-001 ENSP00000342981 ENST00000340339	Q8IZF4 [Direct mapping] Adhesion G-protein coupled receptor G5 A0A024R6S3 [Target identity:100%; Query identity:100%] G protein-coupled receptor 114, isoform CRA_a Show all	G-protein coupled receptors GPCRs excl olfactory receptors Family 2 (B) receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0007166 [cell surface receptor signaling pathway] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	528 aa 59 kDa	Yes	7
ADGRG5-006 ENSP00000290823 ENST00000349457	Q8IZF4 [Direct mapping] Adhesion G-protein coupled receptor G5 A0A024R6S3 [Target identity:100%; Query identity:100%] G protein-coupled receptor 114, isoform CRA_a Show all	G-protein coupled receptors GPCRs excl olfactory receptors Family 2 (B) receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0007166 [cell surface receptor signaling pathway] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	528 aa 59 kDa	Yes	7
ADGRG5-009 ENSP00000482481 ENST00000615867	A0A087WZA0 [Direct mapping] Adhesion G-protein-coupled receptor G5 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		221 aa 24.8 kDa	Yes	0