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Thyroid cancers along with few cases of gliomas, colorectal and pancreatic cancers displayed moderate cytoplasmic positivity with additional membranous staining in occasional cases. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
IP6K3 (HGNC Symbol)
Synonyms
IHPK3, INSP6K3
Description
Inositol hexakisphosphate kinase 3 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]