Cell atlas - C3orf17 - The Human Protein Atlas

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C3orf17

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	C3orf17
Gene description	Chromosome 3 open reading frame 17
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus & nucleoli.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported), Nucleoli (supported)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA069654
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus & nucleoli.

Main location

Nucleus (supported), Nucleoli (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA069654	HaCaT	Nucleus	Intensity
	HPA069654	HaCaT	Nucleoli
	HPA069654	U-2 OS	Nucleus	Intensity
	HPA069654	U-2 OS	Nucleoli

GENE INFORMATION
Gene name	C3orf17 (HGNC Symbol)
Synonyms	DKFZP434F2021, NET17
Description	Chromosome 3 open reading frame 17 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q13.2
Chromosome location (bp)	113002440 - 113019861
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163608 (version 83.38)
Entrez gene	25871
UniProt	Q6NW34 (UniProt - Evidence at protein level)
neXtProt	NX_Q6NW34
Antibodypedia	C3orf17 antibodies

PROTEIN BROWSER

C3orf17-001	C3orf17-002	C3orf17-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C3orf17-001 ENSP00000320251 ENST00000314400	Q6NW34 [Direct mapping] Uncharacterized protein C3orf17 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0016021 [integral component of membrane] GO:0045665 [negative regulation of neuron differentiation] GO:0045747 [positive regulation of Notch signaling pathway] Show all	567 aa 64.6 kDa	No	1
C3orf17-002 ENSP00000373173 ENST00000383675	Q6NW34 [Direct mapping] Uncharacterized protein C3orf17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	497 aa 56.7 kDa	No	0
C3orf17-015 ENSP00000417613 ENST00000472166	C9J9E3 [Direct mapping] Uncharacterized protein C3orf17 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		81 aa 9.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.