Tissue expression of DPY19L2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	DPY19L2
Gene description	Dpy-19-like 2 (C. elegans)
Protein class	Disease related genes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Mixed
FANTOM5:	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION
Gene name	DPY19L2 (HGNC Symbol)
Synonyms	FLJ32949, SPATA34
Description	Dpy-19-like 2 (C. elegans) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9). [provided by RefSeq, Dec 2011]
Chromosome	12
Cytoband	q14.2
Chromosome location (bp)	63558913 - 63668939
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177990 (version 83.38)
Entrez gene	283417
UniProt	Q6NUT2 (UniProt - Evidence at protein level)
neXtProt	NX_Q6NUT2
Antibodypedia	DPY19L2 antibodies

PROTEIN BROWSER

DPY19L2-001	DPY19L2-005	DPY19L2-006	DPY19L2-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DPY19L2-001 ENSP00000315988 ENST00000324472	Q6NUT2 [Direct mapping] Probable C-mannosyltransferase DPY19L2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0000030 [mannosyltransferase activity] GO:0005634 [nucleus] GO:0005637 [nuclear inner membrane] GO:0007275 [multicellular organismal development] GO:0007286 [spermatid development] GO:0016021 [integral component of membrane] GO:0018406 [protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan] Show all	758 aa 87.4 kDa	No	>9
DPY19L2-005 ENSP00000444932 ENST00000542209	F5H4G6 [Direct mapping] Probable C-mannosyltransferase DPY19L2 Show all	Predicted intracellular proteins Show all	GO:0000030 [mannosyltransferase activity] GO:0005637 [nuclear inner membrane] GO:0018406 [protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan] Show all	90 aa 9.9 kDa	No	0
DPY19L2-006 ENSP00000439567 ENST00000538147	F5H1L7 [Direct mapping] Probable C-mannosyltransferase DPY19L2 Show all	Predicted intracellular proteins Show all	GO:0000030 [mannosyltransferase activity] GO:0005637 [nuclear inner membrane] GO:0007286 [spermatid development] GO:0016021 [integral component of membrane] GO:0018406 [protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan] Show all	47 aa 5.7 kDa	No	0
DPY19L2-007 ENSP00000443126 ENST00000541083	F5H5T7 [Direct mapping] Probable C-mannosyltransferase DPY19L2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0000030 [mannosyltransferase activity] GO:0005637 [nuclear inner membrane] GO:0016021 [integral component of membrane] GO:0018406 [protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan] Show all	125 aa 14.5 kDa	No	5