Cell atlas - FAM72A - The Human Protein Atlas

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FAM72A

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane
	Vesicles

Human cell
	Cytosol
	Plasma Membrane
	Vesicles

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GENERAL INFORMATION
Gene name	FAM72A
Gene description	Family with sequence similarity 72, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to vesicles. In addition localized to the plasma membrane & cytosol. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)
Additional location	In addition localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA043271 , HPA067321
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to vesicles. In addition localized to the plasma membrane & cytosol. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Vesicles (approved)

Additional location

Plasma membrane (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA043271	A-431	Vesicles
HPA043271	A-431	Cytosol
HPA043271	PC-3	No staining
HPA043271	U-2 OS	Vesicles
HPA043271	U-2 OS	Cytosol
HPA067321	A-431	Vesicles
HPA067321	U-2 OS	Vesicles
HPA067321	U-251 MG	Vesicles
HPA067321	U-251 MG	Plasma membrane

GENE INFORMATION
Gene name	FAM72A (HGNC Symbol)
Synonyms	MGC57827, RP11-312O7.1
Description	Family with sequence similarity 72, member A (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q32.1
Chromosome location (bp)	206186179 - 206204414
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196550 (version 83.38)
Entrez gene	729533
UniProt	Q5TYM5 (UniProt - Evidence at protein level)
neXtProt	NX_Q5TYM5
Antibodypedia	FAM72A antibodies

PROTEIN BROWSER

FAM72A-001	FAM72A-002	FAM72A-003	FAM72A-006	FAM72A-007	FAM72A-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM72A-001 ENSP00000356096 ENST00000367128	Q5TYM5 [Direct mapping] Protein FAM72A Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] Show all	149 aa 16.6 kDa	No	0
FAM72A-002 ENSP00000340661 ENST00000341209	Q5TYM5 [Direct mapping] Protein FAM72A Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] Show all	109 aa 12.2 kDa	No	0
FAM72A-003 ENSP00000475292 ENST00000431655	U3KPW2 [Direct mapping] Protein FAM72A Show all	Predicted intracellular proteins Show all		120 aa 13.4 kDa	No	0
FAM72A-006 ENSP00000356097 ENST00000367129	Q5TYM6 [Direct mapping] Family with sequence similarity 72, member A; Protein FAM72A Show all	Predicted intracellular proteins Show all		149 aa 16.4 kDa	No	0
FAM72A-007 ENSP00000476019 ENST00000468509	U3KQM2 [Direct mapping] Protein FAM72A Show all	Predicted intracellular proteins Show all		70 aa 7.4 kDa	No	0
FAM72A-008 ENSP00000475410 ENST00000607379	U3KQ03 [Direct mapping] Protein FAM72A Show all	Predicted intracellular proteins Show all		51 aa 5.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.