Cell atlas - EFCAB2 - The Human Protein Atlas

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EFCAB2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	EFCAB2
Gene description	EF-hand calcium binding domain 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA031206
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol.

Main location

Plasma membrane (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA031206	A-431	Plasma membrane
	HPA031206	A-431	Cytosol
	HPA031206	U-2 OS	Plasma membrane
			Mitochondria
			Cytosol
	HPA031206	U-251 MG	Plasma membrane
	HPA031206	U-251 MG	Cytosol

GENE INFORMATION
Gene name	EFCAB2 (HGNC Symbol)
Synonyms	CFAP200, DRC8, MGC12458
Description	EF-hand calcium binding domain 2 (HGNC Symbol)
Entrez gene summary	The gene encodes a protein that contains two EF-hand calcium-binding domains although its function has yet to be determined. Alternatively spliced transcripts have been observed. [provided by RefSeq, Mar 2014]
Chromosome	1
Cytoband	q44
Chromosome location (bp)	244969705 - 245127164
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203666 (version 83.38)
Entrez gene	84288
UniProt	Q5VUJ9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5VUJ9
Antibodypedia	EFCAB2 antibodies

PROTEIN BROWSER

EFCAB2-001	EFCAB2-003	EFCAB2-007	EFCAB2-008	EFCAB2-010	EFCAB2-012	EFCAB2-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EFCAB2-001 ENSP00000355479 ENST00000366522	Q5VUJ9 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	269 aa 29.7 kDa	No	0
EFCAB2-003 ENSP00000355480 ENST00000366523	Q5VUJ9 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	162 aa 18.9 kDa	No	0
EFCAB2-007 ENSP00000355478 ENST00000366521	H7BY53 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	221 aa 25.3 kDa	No	0
EFCAB2-008 ENSP00000405269 ENST00000425550	H0Y6F0 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	127 aa 14.6 kDa	No	0
EFCAB2-010 ENSP00000397120 ENST00000427529	H0Y588 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	52 aa 5.7 kDa	No	0
EFCAB2-012 ENSP00000408661 ENST00000447569	Q5VUJ9 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	133 aa 15.5 kDa	No	0
EFCAB2-015 ENSP00000447807 ENST00000551317	H0YHT5 [Direct mapping] EF-hand calcium-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] Show all	131 aa 15.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.