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Most cancer tissues showed weak to moderate cytoplasmic positivity. A few urothelial, colorectal and stomach cancers exhibited strong immunoreactivity. Malignant gliomas, lymphomas, carcinoids and renal cell carcinomas were negative.
GENE INFORMATION
Gene name
GBP7 (HGNC Symbol)
Synonyms
FLJ38822, GBP4L
Description
Guanylate binding protein 7 (HGNC Symbol)
Entrez gene summary
Guanylate-binding proteins, such as GBP7, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008]