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GRXCR1

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GENERAL INFORMATION

Gene name

 GRXCR1

Gene description

 Glutaredoxin, cysteine rich 1

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 GRXCR1 (HGNC Symbol)

Synonyms

 DFNB25, PPP1R88

Description

 Glutaredoxin, cysteine rich 1 (HGNC Symbol)

Entrez gene summary

 This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010]

Chromosome

 4

Cytoband

 p13

Chromosome location (bp)

 42893267 - 43030658

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000215203 (version 83.38)

Entrez gene

 389207

UniProt

 A8MXD5 (UniProt - Evidence at protein level)

neXtProt

 NX_A8MXD5

Antibodypedia

 GRXCR1 antibodies

PROTEIN BROWSER
GRXCR1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GRXCR1-001
ENSP00000382670
ENST00000399770
A8MXD5 [Direct mapping]
Glutaredoxin domain-containing cysteine-rich protein 1
Show all
Predicted intracellular proteins
Disease related genes
Show all
GO:0003674 [molecular_function]
GO:0007605 [sensory perception of sound]
GO:0009055 [electron carrier activity]
GO:0010923 [negative regulation of phosphatase activity]
GO:0015035 [protein disulfide oxidoreductase activity]
GO:0032420 [stereocilium]
GO:0042491 [auditory receptor cell differentiation]
GO:0045454 [cell redox homeostasis]
GO:0048563 [post-embryonic organ morphogenesis]
GO:0048839 [inner ear development]
GO:0055114 [oxidation-reduction process]
GO:0060091 [kinocilium]
GO:0060118 [vestibular receptor cell development]
GO:0060119 [inner ear receptor cell development]
GO:0060122 [inner ear receptor stereocilium organization]
Show all
 290 aa
32.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.