Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS TPM TPM max in non-specific ADCYAP1R1 PAC1, PAC1R, PACAPR ENSG00000078549 Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7 31052461-31111479 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA049877 Approved Uncertain Vesicles Tissue enhanced 0 cerebral cortex: 137.5;fallopian tube: 46.5 cervix: 20.6 ADGRA1 GPR123, KIAA1828 ENSG00000197177 Adhesion G protein-coupled receptor A1 10 133070929-133131675 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA042773 Approved Tissue enhanced 0 adrenal gland: 4.9;cerebral cortex: 22.5 fallopian tube: 3.1 ADGRA2 DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5 ENSG00000020181 Adhesion G protein-coupled receptor A2 8 37784191-37844896 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA012393 Uncertain Expressed in all seminal vesicle: 86.1 ADGRA3 FLJ38547, GPR125, PGR21 ENSG00000152990 Adhesion G protein-coupled receptor A3 4 22345071-22516054 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA008904 Uncertain Expressed in all thyroid gland: 42.3 ADGRB2 BAI2 ENSG00000121753 Adhesion G protein-coupled receptor B2 1 31727117-31764893 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052612, HPA054617 Supported Centrosome Tissue enriched 14 cerebral cortex: 72.5 adrenal gland: 5.1 ADGRD1 DKFZp434B1272, GPR133, PGR25 ENSG00000111452 Adhesion G protein-coupled receptor D1 12 130953907-131141469 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA042395 Uncertain Approved Nucleus
Cytosol Tissue enhanced 0 placenta: 44.3 lung: 32.7 ADGRE1 EMR1, TM7LN3 ENSG00000174837 Adhesion G protein-coupled receptor E1 19 6887566-6940459 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA052809 Uncertain Tissue enhanced 0 appendix: 10.2;spleen: 20.1 lung: 6.8 ADGRE2 CD312, EMR2 ENSG00000127507 Adhesion G protein-coupled receptor E2 19 14732393-14778541 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA055200 Uncertain Vesicles Tissue enhanced 0 appendix: 27.6;spleen: 15.7 adipose tissue: 5.9 ADGRE3 EMR3 ENSG00000131355 Adhesion G protein-coupled receptor E3 19 14619117-14690027 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA015638 Uncertain Tissue enhanced 0 appendix: 8.9;spleen: 8.8 lung: 3.9 ADGRE5 CD97, TM7LN1 ENSG00000123146 Adhesion G protein-coupled receptor E5 19 14380501-14408725 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013707 Supported Approved Cytosol Expressed in all spleen: 142.8 ADGRF1 GPR110, hGPCR36, PGR19 ENSG00000153292 Adhesion G protein-coupled receptor F1 6 46997703-47042363 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA038438 Approved Tissue enhanced 0 esophagus: 14.7;kidney: 17.6;urinary bladder: 19.6 gallbladder: 9.5 ADGRF2 GPR111, hGPCR35, PGR20 ENSG00000164393 Adhesion G protein-coupled receptor F2 6 47656436-47697797 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA035507 Uncertain Tissue enhanced 0 fallopian tube: 1.5;skin: 1.4 esophagus: 0.3 ADGRF3 GPR113, hGPCR37, PGR23 ENSG00000173567 Adhesion G protein-coupled receptor F3 2 26308173-26346817 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA044500 Uncertain Not detected kidney: 0.9 ADGRF4 FLJ38076, GPR115, PGR18 ENSG00000153294 Adhesion G protein-coupled receptor F4 6 47685864-47722021 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA007131, HPA007158 Supported Uncertain Mitochondria Group enriched 7 esophagus: 12.1;skin: 45.9 tonsil: 3.9 ADGRG1 GPR56, TM7LN4, TM7XN1 ENSG00000205336 Adhesion G protein-coupled receptor G1 16 57610652-57665580 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA046065 Uncertain Expressed in all thyroid gland: 348.2 ADGRG2 EDDM6, GPR64, HE6, TM7LN2 ENSG00000173698 Adhesion G protein-coupled receptor G2 X 18989309-19122637 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001478, HPA050029 Supported Approved Plasma membrane
Cytosol Tissue enriched 6 epididymis: 1469.4 parathyroid gland: 235.5 ADGRG3 GPR97, Pb99, PGR26 ENSG00000182885 Adhesion G protein-coupled receptor G3 16 57668187-57689378 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA040469 Uncertain Group enriched 5 appendix: 19.4;bone marrow: 86.7 adipose tissue: 9.6 ADGRG4 GPR112, PGR17, RP1-299I16 ENSG00000156920 Adhesion G protein-coupled receptor G4 X 136300963-136416888 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at transcript level Evidence at protein level HPA035324 Uncertain Tissue enhanced 0 duodenum: 2.6;small intestine: 1.7 fallopian tube: 0.5 ADGRG5 GPR114, PGR27 ENSG00000159618 Adhesion G protein-coupled receptor G5 16 57542421-57591681 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA007133 Supported Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enhanced 0 lymph node: 11.3;tonsil: 8.9 appendix: 6.2 ADGRG6 FLJ14937, GPR126 ENSG00000112414 Adhesion G protein-coupled receptor G6 6 142301854-142446266 G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA017346 Approved Tissue enhanced 0 placenta: 66.6 liver: 36.9 ADGRL1 CIRL1, KIAA0821, LEC2, LPHN1 ENSG00000072071 Adhesion G protein-coupled receptor L1 19 14147743-14206187 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA037974 Uncertain Tissue enhanced 0 cerebral cortex: 60.3 parathyroid gland: 24.2 ADGRL2 KIAA0786, LEC1, LPHH1, LPHN2 ENSG00000117114 Adhesion G protein-coupled receptor L2 1 81306160-81992436 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043447 Approved Plasma membrane
Cell Junctions Mixed thyroid gland: 72.8 ADGRL3 KIAA0768, LEC3, LPHN3 ENSG00000150471 Adhesion G protein-coupled receptor L3 4 61201258-62078335 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015027, HPA015762, CAB022698 Uncertain Tissue enhanced 0 cerebral cortex: 42.1;parathyroid gland: 30.1 cervix: 8.5 ADGRL4 ELTD1, ETL ENSG00000162618 Adhesion G protein-coupled receptor L4 1 78889764-79006718 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA025229 Supported Mixed adipose tissue: 67.6 ADGRV1 DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1 ENSG00000164199 Adhesion G protein-coupled receptor V1 5 90529344-91164221 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA067503 Approved Group enriched 6 adrenal gland: 56.5;cerebral cortex: 29.1 thyroid gland: 6.6 CALCRL CGRPR, CRLR ENSG00000064989 Calcitonin receptor-like 2 187343129-187448460 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008070, HPA046515 Uncertain Supported Plasma membrane Tissue enhanced 0 lung: 114.4 adipose tissue: 76.3 CELSR1 ADGRC1, CDHF9, FMI2, HFMI2, ME2 ENSG00000075275 Cadherin, EGF LAG seven-pass G-type receptor 1 22 46360834-46537170 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA052976, HPA060521, HPA067269 Uncertain Supported Plasma membrane Mixed fallopian tube: 15.4 CELSR2 ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3 ENSG00000143126 Cadherin, EGF LAG seven-pass G-type receptor 2 1 109250019-109275750 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013952 Uncertain Approved Cytosol Tissue enhanced 0 cerebral cortex: 45.2 skin: 31.1 CELSR3 ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2 ENSG00000008300 Cadherin, EGF LAG seven-pass G-type receptor 3 3 48636469-48662915 G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA062866 Approved Group enriched 6 adrenal gland: 1.6;cerebral cortex: 6.0;testis: 3.6 parathyroid gland: 0.6 CRHR2 CRF-RB, CRF2, HM-CRF ENSG00000106113 Corticotropin releasing hormone receptor 2 7 30651943-30700129 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA046683 Uncertain Tissue enhanced 0 seminal vesicle: 1.8 cerebral cortex: 1.2 GCGR GGR ENSG00000215644 Glucagon receptor 17 81804132-81814013 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA071228 Approved Golgi apparatus Group enriched 7 adrenal gland: 6.6;kidney: 8.5;liver: 20.9;parathyroid gland: 9.4 skin: 1.6 GIPR ENSG00000010310 Gastric inhibitory polypeptide receptor 19 45668244-45683724 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level CAB022710 Uncertain Tissue enhanced 0 stomach: 22.6 parathyroid gland: 12.2 GLP2R ENSG00000065325 Glucagon-like peptide 2 receptor 17 9822206-9892102 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level CAB022690, HPA049244 Supported Supported Plasma membrane Tissue enhanced 0 gallbladder: 19.4 duodenum: 10.4 GPR157 FLJ12132 ENSG00000180758 G protein-coupled receptor 157 1 9100305-9129170 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA028697 Uncertain Uncertain Nucleoli
Plasma membrane
Cell Junctions Mixed parathyroid gland: 23.9 PTH1R PTHR, PTHR1 ENSG00000160801 Parathyroid hormone 1 receptor 3 46877746-46903799 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA007978 Approved Tissue enhanced 0 kidney: 158.5 adrenal gland: 36.8 PTH2R PTHR2 ENSG00000144407 Parathyroid hormone 2 receptor 2 208359714-208854503 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA010655 Approved Mixed bone marrow: 2.9 SCTR ENSG00000080293 Secretin receptor 2 119439843-119525301 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA007269 Uncertain Tissue enhanced 0 duodenum: 27.4;lung: 13.0;pancreas: 14.3 stomach: 4.2 VIPR1 HVR1, RDC1, VPAC1, VPAC1R ENSG00000114812 Vasoactive intestinal peptide receptor 1 3 42489299-42537573 G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level HPA026777 Approved Tissue enhanced 0 lung: 60.0 duodenum: 35.4 VIPR2 VPAC2, VPAC2R ENSG00000106018 Vasoactive intestinal peptide receptor 2 7 159028175-159144957 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA062707 Approved Tissue enhanced 0 seminal vesicle: 28.2 epididymis: 14.8