Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS TPM TPM max in non-specific CASR FHH, GPRC2A, HHC, HHC1, NSHPT ENSG00000036828 Calcium-sensing receptor 3 122183683-122286503 Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039686, HPA050335 Supported Tissue enriched 60 parathyroid gland: 1627.2 kidney: 27.0 GABBR1 GPRC3A, hGB1a ENSG00000204681 Gamma-aminobutyric acid (GABA) B receptor, 1 6 29555629-29633976 FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA050483, HPA058459 Uncertain Uncertain Centrosome Tissue enhanced 0 cerebral cortex: 20.9 spleen: 13.3 GABBR2 GABABR2, GPR51, GPRC3B, HG20 ENSG00000136928 Gamma-aminobutyric acid (GABA) B receptor, 2 9 98288082-98709197 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA013820, HPA031684 Supported Tissue enriched 19 cerebral cortex: 88.4 adrenal gland: 4.6 GPR156 GABABL, PGR28 ENSG00000175697 G protein-coupled receptor 156 3 120164645-120285094 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level HPA028642, HPA028644 Uncertain Supported Plasma membrane Tissue enhanced 0 testis: 5.1 fallopian tube: 1.8 GPR158 KIAA1136 ENSG00000151025 G protein-coupled receptor 158 10 25175062-25602226 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA013185 Uncertain Approved Cytosol Tissue enriched 17 cerebral cortex: 17.9 testis: 1.0 GPRC5A PEIG-1, RAI3, RAIG1, TIG1 ENSG00000013588 G protein-coupled receptor, class C, group 5, member A 12 12890782-12917937 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007928, HPA046526 Approved Validated Vesicles
Plasma membrane Tissue enhanced 0 lung: 302.3 thyroid gland: 90.7 GPRC5B RAIG-2 ENSG00000167191 G protein-coupled receptor, class C, group 5, member B 16 19856691-19886167 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level HPA015247 Approved Supported Nucleus
Nucleoli
Vesicles Tissue enhanced 0 cerebral cortex: 309.2 testis: 66.5 GPRC5C RAIG-3 ENSG00000170412 G protein-coupled receptor, class C, group 5, member C 17 74424851-74451653 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029776 Supported Uncertain Nucleus
Microtubule organizing center
Cytosol Mixed thyroid gland: 103.7 GPRC5D ENSG00000111291 G protein-coupled receptor, class C, group 5, member D 12 12940775-12952147 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA071909 Approved Mixed testis: 5.2 GRM1 GPRC1A, mGlu1, MGLUR1, PPP1R85 ENSG00000152822 Glutamate receptor, metabotropic 1 6 146027646-146437598 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Evidence at transcript level Evidence at protein level HPA015701 Approved Approved Vesicles Tissue enhanced 0 cerebral cortex: 7.1 heart muscle: 1.4 GRM2 GPRC1B, mGlu2, MGLUR2 ENSG00000164082 Glutamate receptor, metabotropic 2 3 51707070-51718613 G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA065166 Approved Tissue enriched 10 cerebral cortex: 4.4 testis: 0.4 GRM4 GPRC1D, mGlu4, MGLUR4 ENSG00000124493 Glutamate receptor, metabotropic 4 6 34018645-34155622 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at transcript level Evidence at protein level CAB022096 Supported Tissue enhanced 0 cerebral cortex: 2.9 testis: 0.7 GRM6 CSNB1B, GPRC1F, mGlu6, MGLUR6 ENSG00000113262 Glutamate receptor, metabotropic 6 5 178978327-178996206 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA014511 Supported Not detected testis: 0.8 GRM7 GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87 ENSG00000196277 Glutamate receptor, metabotropic 7 3 6770001-7741533 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA015964 Uncertain Cytosol Tissue enhanced 0 cerebral cortex: 10.1;parathyroid gland: 7.0 smooth muscle: 3.4 GRM8 GLUR8, GPRC1H, mGlu8, MGLUR8 ENSG00000179603 Glutamate receptor, metabotropic 8 7 126438598-127253294 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA051481 Uncertain Tissue enhanced 0 cerebral cortex: 4.1 testis: 2.9 TAS1R1 GPR70, T1R1, TR1 ENSG00000173662 Taste receptor, type 1, member 1 1 6555181-6579757 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level Evidence at transcript level Evidence at transcript level HPA034579, HPA034580 Approved Tissue enriched 7 testis: 4.2 skin: 0.5 TAS1R3 T1R3 ENSG00000169962 Taste receptor, type 1, member 3 1 1331314-1335306 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Evidence at transcript level Evidence at protein level HPA053439 Approved Group enriched 5 epididymis: 14.7;salivary gland: 3.3 appendix: 1.7