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Moderate to strong cytoplasmic immunoreactivity was observed in cases of non-Hodgkin's lymphomas along with fractions of pancreatic and ovarian cancers. Remaining malignancies were in general negative.
GENE INFORMATION
Gene name
TRAF3IP3 (HGNC Symbol)
Synonyms
T3JAM
Description
TRAF3 interacting protein 3 (HGNC Symbol)
Entrez gene summary
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]