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Colorectal and thyroid cancers as well as most ovarian, breast, cervical, stomach and pancreatic cancer showed moderate to strong immunoreactivity. Additional nuclear positivity was observed in a few cases. A majority of the remaining cancers were weakly stained or negative.
Several hepatocellular carcinomas as well as fractions of cases in pancreatic and urothelial cancer were strongly stained. Cases of prostate cancers and a few melanomas, colorectal and testicular cancers showed moderately positivity. Remaining cancers were in general negative.
GENE INFORMATION
Gene name
DAPP1 (HGNC Symbol)
Synonyms
BAM32
Description
Dual adaptor of phosphotyrosine and 3-phosphoinositides (HGNC Symbol)
J3KNB3 [Direct mapping] Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; Dual adaptor of phosphotyrosine and 3-phosphoinositides, isoform CRA_d
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Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)