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Gene name

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Chromosome

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In atlas

Reliability

Reliability

Reliability

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Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

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Detectable

Cell line

Detectable

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Antibodies

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GGT1
  • premium

    TISSUE

  • CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

GGT1

Gene description

Gamma-glutamyltransferase 1

Protein class

Candidate cardiovascular disease genes
CD markers
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

22
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (kidney)
GTEx:Tissue enhanced (kidney)
FANTOM5:Tissue enhanced (kidney, seminal vesicle)

Protein evidence

Evidence at protein level

Protein expression

Selective cytoplasmic expression in renal tubules of kidney, epididymis, liver and pancreas.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

Supported based on 2 antibodies.
HPA045635 , HPA047534
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Epididymis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney, seminal vesicle)

GENE INFORMATION

Gene name

GGT1 (HGNC Symbol)

Synonyms

CD224, D22S672, D22S732, GGT

Description

Gamma-glutamyltransferase 1 (HGNC Symbol)

Entrez gene summary

The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]

Chromosome

22

Cytoband

q11.23

Chromosome location (bp)

24583750 - 24629005

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100031 (version 83.38)

Entrez gene

2678

UniProt

P19440 (UniProt - Evidence at protein level)

neXtProt

NX_P19440

Antibodypedia

GGT1 antibodies

PROTEIN BROWSER

«
GGT1-001
GGT1-002
GGT1-003
GGT1-004
GGT1-005
GGT1-010
GGT1-011
GGT1-012
GGT1-013
GGT1-014
GGT1-015
GGT1-016
GGT1-017
GGT1-018
GGT1-019
GGT1-020
GGT1-023
GGT1-024
GGT1-025
GGT1-026
GGT1-027
GGT1-028
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GGT1-001
ENSP00000383231
ENST00000400380
P19440 [Direct mapping]
Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain
Show all
Enzymes
   ENZYME proteins
   Transferases
   Hydrolases
CD markers
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Candidate cardiovascular disease genes
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002682 [regulation of immune system process]
GO:0003840 [gamma-glutamyltransferase activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005886 [plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006536 [glutamate metabolic process]
GO:0006691 [leukotriene metabolic process]
GO:0006749 [glutathione metabolic process]
GO:0006750 [glutathione biosynthetic process]
GO:0006751 [glutathione catabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007283 [spermatogenesis]
GO:0016021 [integral component of membrane]
GO:0019344 [cysteine biosynthetic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019370 [leukotriene biosynthetic process]
GO:0031362 [anchored component of external side of plasma membrane]
GO:0031638 [zymogen activation]
GO:0036374 [glutathione hydrolase activity]
GO:0044281 [small molecule metabolic process]
GO:0050727 [regulation of inflammatory response]
GO:0070062 [extracellular exosome]
GO:1901687 [glutathione derivative biosynthetic process]
Show all
569 aa
61.4 kDa
Yes 1
GGT1-002
ENSP00000383232
ENST00000400382
P19440 [Direct mapping]
Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain
Show all
Enzymes
   ENZYME proteins
   Transferases
   Hydrolases
CD markers
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Candidate cardiovascular disease genes
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002682 [regulation of immune system process]
GO:0003840 [gamma-glutamyltransferase activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005886 [plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006536 [glutamate metabolic process]
GO:0006691 [leukotriene metabolic process]
GO:0006749 [glutathione metabolic process]
GO:0006750 [glutathione biosynthetic process]
GO:0006751 [glutathione catabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007283 [spermatogenesis]
GO:0016021 [integral component of membrane]
GO:0019344 [cysteine biosynthetic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019370 [leukotriene biosynthetic process]
GO:0031362 [anchored component of external side of plasma membrane]
GO:0031638 [zymogen activation]
GO:0036374 [glutathione hydrolase activity]
GO:0044281 [small molecule metabolic process]
GO:0050727 [regulation of inflammatory response]
GO:0070062 [extracellular exosome]
GO:1901687 [glutathione derivative biosynthetic process]
Show all
569 aa
61.4 kDa
Yes 1
GGT1-003
ENSP00000393537
ENST00000412658
E7ET76 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
463 aa
50.1 kDa
Yes 1
GGT1-004
ENSP00000415553
ENST00000452551
E7ETJ6 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
127 aa
13.4 kDa
Yes 1
GGT1-005
ENSP00000248923
ENST00000248923
P19440 [Direct mapping]
Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain
Show all
Enzymes
   ENZYME proteins
   Transferases
   Hydrolases
CD markers
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Candidate cardiovascular disease genes
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002682 [regulation of immune system process]
GO:0003840 [gamma-glutamyltransferase activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005886 [plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006536 [glutamate metabolic process]
GO:0006691 [leukotriene metabolic process]
GO:0006749 [glutathione metabolic process]
GO:0006750 [glutathione biosynthetic process]
GO:0006751 [glutathione catabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007283 [spermatogenesis]
GO:0016021 [integral component of membrane]
GO:0019344 [cysteine biosynthetic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019370 [leukotriene biosynthetic process]
GO:0031362 [anchored component of external side of plasma membrane]
GO:0031638 [zymogen activation]
GO:0036374 [glutathione hydrolase activity]
GO:0044281 [small molecule metabolic process]
GO:0050727 [regulation of inflammatory response]
GO:0070062 [extracellular exosome]
GO:1901687 [glutathione derivative biosynthetic process]
Show all
569 aa
61.4 kDa
Yes 1
GGT1-010
ENSP00000415129
ENST00000456869
C9JGF3 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
30 aa
3.2 kDa
No 0
GGT1-011
ENSP00000389935
ENST00000411974
E7ENJ5 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
120 aa
12.6 kDa
Yes 1
GGT1-012
ENSP00000393135
ENST00000445029
E9PHP2 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
68 aa
7.1 kDa
Yes 0
GGT1-013
ENSP00000395271
ENST00000419133
E7ETR7 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
174 aa
18.5 kDa
Yes 1
GGT1-014
ENSP00000408151
ENST00000412898
E7ERN9 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
80 aa
8.3 kDa
Yes 0
GGT1-015
ENSP00000415024
ENST00000455483
E7ETN1 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
98 aa
10.1 kDa
Yes 1
GGT1-016
ENSP00000400621
ENST00000447416
E7EM62 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
126 aa
13.2 kDa
Yes 1
GGT1-017
ENSP00000398589
ENST00000432867
E7ETU4 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
111 aa
11.5 kDa
Yes 1
GGT1-018
ENSP00000387796
ENST00000451366
E7EVF8 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
116 aa
12.1 kDa
Yes 1
GGT1-019
ENSP00000403826
ENST00000438643
C9JIY6 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
37 aa
4 kDa
Yes 0
GGT1-020
ENSP00000415068
ENST00000428855
E7EM62 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
126 aa
13.2 kDa
Yes 1
GGT1-023
ENSP00000417044
ENST00000430289
E7ESL5 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
109 aa
11.4 kDa
Yes 1
GGT1-024
ENSP00000384820
ENST00000403838
P19440 [Direct mapping]
Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain
Show all
Enzymes
   ENZYME proteins
   Transferases
   Hydrolases
CD markers
Predicted intracellular proteins
Plasma proteins
Candidate cardiovascular disease genes
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002682 [regulation of immune system process]
GO:0003840 [gamma-glutamyltransferase activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005886 [plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006536 [glutamate metabolic process]
GO:0006691 [leukotriene metabolic process]
GO:0006749 [glutathione metabolic process]
GO:0006750 [glutathione biosynthetic process]
GO:0006751 [glutathione catabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007283 [spermatogenesis]
GO:0016021 [integral component of membrane]
GO:0019344 [cysteine biosynthetic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019370 [leukotriene biosynthetic process]
GO:0031362 [anchored component of external side of plasma membrane]
GO:0031638 [zymogen activation]
GO:0036374 [glutathione hydrolase activity]
GO:0044281 [small molecule metabolic process]
GO:0050727 [regulation of inflammatory response]
GO:0070062 [extracellular exosome]
GO:1901687 [glutathione derivative biosynthetic process]
Show all
225 aa
24.1 kDa
No 0
GGT1-025
ENSP00000384381
ENST00000401885
P19440 [Direct mapping]
Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain
Show all
Enzymes
   ENZYME proteins
   Transferases
   Hydrolases
CD markers
Predicted intracellular proteins
Plasma proteins
Candidate cardiovascular disease genes
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002682 [regulation of immune system process]
GO:0003840 [gamma-glutamyltransferase activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005886 [plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006536 [glutamate metabolic process]
GO:0006691 [leukotriene metabolic process]
GO:0006749 [glutathione metabolic process]
GO:0006750 [glutathione biosynthetic process]
GO:0006751 [glutathione catabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007283 [spermatogenesis]
GO:0016021 [integral component of membrane]
GO:0019344 [cysteine biosynthetic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019370 [leukotriene biosynthetic process]
GO:0031362 [anchored component of external side of plasma membrane]
GO:0031638 [zymogen activation]
GO:0036374 [glutathione hydrolase activity]
GO:0044281 [small molecule metabolic process]
GO:0050727 [regulation of inflammatory response]
GO:0070062 [extracellular exosome]
GO:1901687 [glutathione derivative biosynthetic process]
Show all
225 aa
24.1 kDa
No 0
GGT1-026
ENSP00000385445
ENST00000404532
P19440 [Direct mapping]
Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 heavy chain Gamma-glutamyltranspeptidase 1 light chain
Show all
Enzymes
   ENZYME proteins
   Transferases
   Hydrolases
CD markers
Predicted intracellular proteins
Plasma proteins
Candidate cardiovascular disease genes
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002682 [regulation of immune system process]
GO:0003840 [gamma-glutamyltransferase activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005886 [plasma membrane]
GO:0006520 [cellular amino acid metabolic process]
GO:0006536 [glutamate metabolic process]
GO:0006691 [leukotriene metabolic process]
GO:0006749 [glutathione metabolic process]
GO:0006750 [glutathione biosynthetic process]
GO:0006751 [glutathione catabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007283 [spermatogenesis]
GO:0016021 [integral component of membrane]
GO:0019344 [cysteine biosynthetic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019370 [leukotriene biosynthetic process]
GO:0031362 [anchored component of external side of plasma membrane]
GO:0031638 [zymogen activation]
GO:0036374 [glutathione hydrolase activity]
GO:0044281 [small molecule metabolic process]
GO:0050727 [regulation of inflammatory response]
GO:0070062 [extracellular exosome]
GO:1901687 [glutathione derivative biosynthetic process]
Show all
225 aa
24.1 kDa
No 0
GGT1-027
ENSP00000385001
ENST00000404920
B5MC36 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
218 aa
23.6 kDa
No 0
GGT1-028
ENSP00000385016
ENST00000404223
B5MC34 [Direct mapping]
Gamma-glutamyltranspeptidase 1
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003840 [gamma-glutamyltransferase activity]
GO:0006749 [glutathione metabolic process]
Show all
252 aa
27 kDa
No 0

Contact

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  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.