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Malignant cells displayed moderate to strong nuclear immunoractivity.
GENE INFORMATION
Gene name
STAG1 (HGNC Symbol)
Synonyms
SA-1, SA1, SCC3A
Description
Stromal antigen 1 (HGNC Symbol)
Entrez gene summary
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle] GO:0000775 [chromosome, centromeric region] GO:0000785 [chromatin] GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003682 [chromatin binding] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005694 [chromosome] GO:0005829 [cytosol] GO:0006366 [transcription from RNA polymerase II promoter] GO:0007059 [chromosome segregation] GO:0007067 [mitotic nuclear division] GO:0016925 [protein sumoylation] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0051301 [cell division]