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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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HRSP12
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    TISSUE

  • CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

HRSP12

Gene description

Heat-responsive protein 12

Protein class

Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Group enriched (liver, kidney)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Selective expression in a few cell types, most abundant in hepatocytes and proximal renal tubules.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 2 antibodies.
HPA022856 , HPA023489
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (liver, kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

HRSP12 (HGNC Symbol)

Synonyms

P14.5, PSP, UK114

Description

Heat-responsive protein 12 (HGNC Symbol)

Entrez gene summary

Chromosome

8

Cytoband

q22.2

Chromosome location (bp)

98102344 - 98117241

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132541 (version 83.38)

Entrez gene

10247

UniProt

P52758 (UniProt - Evidence at protein level)

neXtProt

NX_P52758

Antibodypedia

HRSP12 antibodies

PROTEIN BROWSER

HRSP12-001
HRSP12-003
HRSP12-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HRSP12-001
ENSP00000254878
ENST00000254878
P52758 [Direct mapping]
Ribonuclease UK114
A0A024R9H2 [Target identity:100%; Query identity:100%]
Heat-responsive protein 12, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001822 [kidney development]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005777 [peroxisome]
GO:0005829 [cytosol]
GO:0006449 [regulation of translational termination]
GO:0007420 [brain development]
GO:0016892 [endoribonuclease activity, producing 3'-phosphomonoesters]
GO:0017148 [negative regulation of translation]
GO:0019239 [deaminase activity]
GO:0030324 [lung development]
GO:0033993 [response to lipid]
GO:0036041 [long-chain fatty acid binding]
GO:0042803 [protein homodimerization activity]
GO:0043167 [ion binding]
GO:0044822 [poly(A) RNA binding]
GO:0046914 [transition metal ion binding]
GO:0050680 [negative regulation of epithelial cell proliferation]
GO:0070062 [extracellular exosome]
GO:0070314 [G1 to G0 transition]
GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic]
GO:1902074 [response to salt]
GO:1904012 [platinum binding]
GO:1904013 [xenon atom binding]
Show all
137 aa
14.5 kDa
No 0
HRSP12-003
ENSP00000430482
ENST00000521560
H0YBX3 [Direct mapping]
Ribonuclease UK114
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process]
GO:0019239 [deaminase activity]
Show all
127 aa
13.7 kDa
Yes 0
HRSP12-007
ENSP00000428596
ENST00000520507
H0YB34 [Direct mapping]
Ribonuclease UK114
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0008152 [metabolic process]
GO:0019239 [deaminase activity]
Show all
148 aa
15.9 kDa
No 0

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.